Evidence map›Paper›PMID 39092646›Full record

ReviewCurrent topics in medicinal chemistry2025

Drug Delivery Systems for Natural Medicines in Cancer Therapy.

P K Hashim, Naseef Punnoth Poonkuzhi, Nusaiba Madappuram Cheruthu, Mohamed Saher Kuruniyan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

P K HashimResearch Institute for Electronic Science, Hokkaido University, Kita 20, Nishi 10, Kita-ku, Sapporo, Hokkaido, 001-0020, Japan.ORCID 0000-0001-9944-7926
Naseef Punnoth PoonkuzhiDepartment of Pharmaceutics, Moulana College of Pharmacy, Perinthelmanna, Kerala, India.
Nusaiba Madappuram CheruthuResearch Institute for Electronic Science, Hokkaido University, Kita 20, Nishi 10, Kita-ku, Sapporo, Hokkaido, 001-0020, Japan.
Mohamed Saher KuruniyanDepartment of Dental Technology, College of Applied Medical Science, King Khalid University, Abha, Kingdom of Saudi Arabia (KSA).

Funding

Deanship of Scientific Research at King Khalid University, Saudi Arabia RGP2/475/45
6 · The paper itself

Abstract

Cancer stands as a prominent global cause of mortality, with chemotherapy using synthetic drugs being the predominant treatment method. Despite its high success rate, this approach is constrained by substantial side effects. Herbal medicines, known for their diverse bioactive components, exhibit promising anticancer attributes. The drug delivery systems can improve the precision of delivering these herbal compounds, enhancing efficacy while minimizing potential side effects. Various platforms, such as nanoparticle-based carriers, liposomes, and polymeric micelles, are investigated for encapsulating and delivering herbal components to cancer cells. These systems not only enhance the bioavailability of herbal compounds but also facilitate controlled release, sustained drug circulation, and improved cellular uptake. This comprehensive review focuses on the recent advancement in the field of drug delivery systems employed in the delivery of plant-derived anticancer compounds. It categorizes carriers into organic and inorganic nanoparticles, addressing their application in enhancing the safety and efficacy of plant-derived anticancer compounds alongside associated challenges. The review concludes by outlining recent investigations into drug delivery systems aimed at increasing the efficacy of plant-derived anticancer compounds. Future research in this field should emphasize experiments in animal models and potential clinical translation.

Indexed as

Antineoplastic AgentsAntineoplastic Agents, PhytogenicBiological ProductsDrug Delivery SystemsNeoplasmsAnimalsDrug CarriersHumansNanoparticlesAntineoplastic AgentsAntineoplastic Agents, PhytogenicBiological ProductsDrug CarriersAnticancer therapyDrug delivery systemsliposomesMicellesNanoparticlesPlant-derived anticancer compoundsPolymerosomes.

Identifiers

PMID39092646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.