Evidence map›Paper›PMID 39092322›Full record

ArticleCureus2024

Higher Onset of Periprosthetic Joint Infections in Patients With Teeth Compared to Those Without Teeth.

Joseph D Brenner, Marina Atallah, David Yatsonsky, Andrew Casabianca, Maged Hanna

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Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Joseph D BrennerCollege of Medicine and Life Sciences, The University of Toledo, Toledo, USA.
Marina AtallahCollege of Medicine and Life Sciences, The University of Toledo, Toledo, USA.
David YatsonskyOrthopedic Surgery, The University of Toledo Medical Center, Toledo, USA.
Andrew CasabiancaAnesthesiology, ProMedica Toledo Hospital, Toledo, USA.
Maged HannaOrthopedic Surgery, The University of Toledo Medical Center, Toledo, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBacteria can enter the bloodstream through simple actions such as brushing teeth, flossing, and even chewing food, increasing the chance of hematogenous seeding of prosthetic joints. Antibiotics before dental work in patients with orthopedic hardware is a topic of debate because of concerns for antibiotic resistance. Patients with dentures theoretically avoid this risk due to the lack of teeth and their maintenance. Most periprosthetic joint infections (PJIs) that occur in the first six months after surgery are due to wound infection, whereas late PJIs are more commonly caused by hematogenous seeding. MATERIALS AND

methodsCharts from patients who received primary total joint arthroplasty were interrogated for the condition of their teeth at the time of operation. If the patient had a PJI, the time from surgery and the organism responsible were noted. Multivariate linear regressions were performed for statistical analysis to compare rates of dental status, infection, comorbidities, and demographics.

resultsFrom the 1,500 charts reviewed, patients with teeth and edentulous had similar rates of comorbidities. PJI patients had higher rates of chronic kidney disease than patients who did not have the infection. The overall rate of infections in patients with teeth was 2.14%, close to the national average. The rate of infection in patients without teeth was 0.78%. Patients with teeth have a higher rate of infection one month or longer from surgery than edentulous patients.

conclusionsThere was an increased infection rate in patients with teeth at six months and greater since the primary total joint arthroplasty. The organisms responsible for many of the PJIs are commonly found in the mouth of humans. Having teeth is a potential risk factor for late PJI.

Indexed as

edentulous patientsoral microbiomeperiprosthetic joint infectionprimary total hip arthroplastyprimary total knee arthroplasty

Identifiers

PMID39092322
PMCPMC11293887

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