Evidence map›Paper›PMID 39092234›Full record

ReviewFrontiers in pharmacology2024

Harnessing the power of bee venom for therapeutic and regenerative medical applications: an updated review.

Kadry M Sadek, Naira A Shib, Ehab S Taher, Fatema Rashed, Mustafa Shukry, Gamal A Atia, Noha Taymour, Mohammad El-Nablaway, Ateya M Ibrahim, Mahmoud M Ramadan and 6 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
  5. Article
  6. Exploratory proteomic characterization ofFrontiers in pharmacology · 2026
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  15. Article
  16. The Anti-Leukemic Potential of Bee Venom.International journal of general medicine · 2025
    Review
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kadry M SadekDepartment of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Naira A ShibDepartment of Biochemistry, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
Ehab S TaherDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
Fatema RashedDepartment of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
Mustafa ShukryDepartment of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Gamal A AtiaDepartment of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
Noha TaymourDepartment of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mohammad El-NablawayDepartment of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia.
Ateya M IbrahimDepartment of Administration and Nursing Education, College of Nursing, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Mahmoud M RamadanDepartment of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates.
Afaf AbdelkaderDepartment of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Benha University, Benha, Egypt.
Mohamed AbdoDepartment of Animal Histology and Anatomy, School of Veterinary Medicine, Badr University in Cairo (BUC), Badr City, Egypt.
Ilinca ImbreaDepartment of Forestry, Faculty of Engineering and Applied Technologies, University of Life Sciences "King Mihai I" from Timisoara, Timisoara, Romania.
Elena PetDepartment of Management and Rural Development, Faculty of Management and Rural Tourism, University of Life Sciences "King Mihai I" from Timisoara, Timisoara, Romania.
Lashin S AliDepartment of Basic Medical Sciences, Faculty of Dentistry, Al-Ahliyya Amman University, Amman, Jordan.
Ahmed AbdeenDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Honeybees have been helpful insects since ancient centuries, and this benefit is not limited to being a honey producer only. After the bee stings a person, pain, and swelling occur in this place, due to the effects of bee venom (BV). This is not a poison in the total sense of the word because it has many benefits, and this is due to its composition being rich in proteins, peptides, enzymes, and other types of molecules in low concentrations that show promise in the treatment of numerous diseases and conditions. BV has also demonstrated positive effects against various cancers, antimicrobial activity, and wound healing versus the human immunodeficiency virus (HIV). Even though topical BV therapy is used to varying degrees among countries, localized swelling or itching are common side effects that may occur in some patients. This review provides an in-depth analysis of the complex chemical composition of BV, highlighting the diverse range of bioactive compounds and their therapeutic applications, which extend beyond the well-known anti-inflammatory and pain-relieving effects, showcasing the versatility of BV in modern medicine. A specific search strategy was followed across various databases; Web of sciences, Scopus, Medline, and Google Scholar including

Indexed as

anticanceranti-inflammationantimicrobialapitherapyneuroprotectionwound healing

Identifiers

PMID39092234
PMCPMC11291246

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.