Evidence map›Paper›PMID 39092172›Full record

ArticleiScience2024

The role of HnrnpF/H as a driver of oligoteratozoospermia.

Jacob K Netherton, Rachel A Ogle, Benjamin R Robinson, Mark Molloy, Christoph Krisp, Tony Velkov, Franca Casagranda, Nicole Dominado, Ana Izabel Silva Balbin Villaverde, Xu Dong Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jacob K NethertonSchool of Biomedical Sciences and Pharmacy, Faculty of Medicine and Health, University of Newcastle, Callaghan, NSW 2308, Australia.
Rachel A OgleSchool of Biomedical Sciences and Pharmacy, Faculty of Medicine and Health, University of Newcastle, Callaghan, NSW 2308, Australia.
Benjamin R RobinsonSchool of Biomedical Sciences and Pharmacy, Faculty of Medicine and Health, University of Newcastle, Callaghan, NSW 2308, Australia.
Mark MolloyAustralian Proteome Analysis Facility, Department of Biomolecular Sciences, Macquarie University, NSW 2109 Australia.
Christoph KrispAustralian Proteome Analysis Facility, Department of Biomolecular Sciences, Macquarie University, NSW 2109 Australia.
Tony VelkovBiomedicine Discovery Institute, Infection & Immunity Program and Department of Microbiology, Monash University, Clayton, VIC 3168, Australia.
Franca CasagrandaDepartment of Anatomy and Physiology, University of Melbourne, Parkville, VIC 3010, Australia.
Nicole DominadoDepartment of Anatomy and Physiology, University of Melbourne, Parkville, VIC 3010, Australia.
Ana Izabel Silva Balbin VillaverdeInstitute of Biological and Natural Sciences, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil.
Xu Dong ZhangSchool of Biomedical Sciences and Pharmacy, Faculty of Medicine and Health, University of Newcastle, Callaghan, NSW 2308, Australia.
Gary R HimeDepartment of Anatomy and Physiology, University of Melbourne, Parkville, VIC 3010, Australia.
Mark A BakerSchool of Biomedical Sciences and Pharmacy, Faculty of Medicine and Health, University of Newcastle, Callaghan, NSW 2308, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Male subfertility or infertility is a common condition often characterized by men producing a low number of sperm with poor quality. To gain insight into this condition, we performed a quantitative proteomic analysis of semen samples obtained from infertile and fertile men. At least 6 proteins showed significant differences in regulation of alternatively spliced isoforms. To investigate this link between aberrant alternative splicing and production of poor-quality spermatozoa, we overexpressed the hnrnpH/F-orthologue Glorund (Glo) in

Indexed as

cell biologyreproductive medicine

Identifiers

PMID39092172
PMCPMC11292545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.