Evidence map›Paper›PMID 39092106›Full record

ArticleChemical science2024

A facile strategy for the construction of a phage display cyclic peptide library for the selection of functional macrocycles.

Hua Xiang, Liwen Bai, Xindan Zhang, Ting Dan, Peng Cheng, Xiaoqin Yang, Honglian Ai, Kai Li, Xinxiang Lei

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Advances in Cyclic Peptides Targeting G Protein-Coupled Receptors.Chembiochem : a European journal of chemical biology · 2026
    Review
  5. Phage Display as a Promising Platform for Peptide Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hua XiangSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.
Liwen BaiSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.
Xindan ZhangSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.
Ting DanSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.
Peng ChengSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.
Xiaoqin YangState Key Laboratory of Applied Organic Chemistry, Lanzhou Magnetic Resonance Center, College of Chemistry and Chemical Engineering, Lanzhou University Lanzhou 730000 China leixx@lzu.edu.cn.
Honglian AiSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.
Kai LiCollege of Life Sciences, South-Central Minzu University Wuhan 430074 China.
Xinxiang LeiSchool of Pharmaceutical Sciences, South-Central Minzu University Wuhan 430074 China.ORCID https://orcid.org/0000-0002-5635-5375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic peptides represent invaluable scaffolds in biological affinity, providing diverse collections for discovering functional molecules targeting challenging biological entities and protein-protein interactions. The field increasingly focuses on developing cyclization strategies and chemically modified combinatorial libraries in conjunction with M13 phage display, to identify macrocyclic peptide inhibitors for traditionally challenging targets. Here, we introduce a cyclization strategy utilizing

Identifiers

PMID39092106
PMCPMC11290325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.