Evidence map›Paper›PMID 39091947›Full record

ArticleHeliyon2024

Long non-coding RNA MIMT1 promotes retinoblastoma proliferation via sponging miR-153-5p to upregulate FGF2.

Bin Wang, Ruyuan Cai, Tingting Sun, Zhufang Yang, Hongjie Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bin WangDepartment of Ophthalmology, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, 75 Juchang Street, Yancheng, 224005, China.
Ruyuan CaiDepartment of Ophthalmology, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, 75 Juchang Street, Yancheng, 224005, China.
Tingting SunDepartment of Ophthalmology, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, 75 Juchang Street, Yancheng, 224005, China.
Zhufang YangDepartment of Ophthalmology, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, 75 Juchang Street, Yancheng, 224005, China.
Hongjie ZhangDepartment of Ophthalmology, Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, 75 Juchang Street, Yancheng, 224005, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rapid development of biotechnology, long non-coding RNAs (lncRNAs) have shown promising potential for cancer treatment and may become novel therapeutic targets. This study aimed to explore the roles of lncRNAs in retinoblastoma (RB). It involves analysing differentially expressed lncRNAs in RB and normal tissues from the GSE111168 and GSE125903 datasets, further validating them in RB cells. Our findings determined that lncRNA MIMT1 was upregulated in RB cell lines and tissues. In WERI-Rb1 and Y79 cells, silencing MIMT1 significantly inhibited cell proliferation, whereas MIMT1 overexpression enhanced cell proliferation. Furthermore,

Indexed as

FGF2lncRNAs MIMT1miR-153-5pRetinoblastoma

Identifiers

PMID39091947
PMCPMC11292528

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.