Evidence map›Paper›PMID 39091843›Full record

ArticlebioRxiv : the preprint server for biology2024

Transiently boosting Vγ9+Vδ2+ γδ T cells early in Mtb coinfection of SIV-infected juvenile macaques does not improve Mtb host resistance.

Erica C Larson, Amy L Ellis, Mark A Rodgers, Abigail K Gubernat, Janelle L Gleim, Ryan V Moriarty, Alexis J Balgeman, Yonne T de Menezes, Cassaundra L Ameel, Daniel J Fillmore and 11 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Erica C LarsonDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-5025-9369
Amy L EllisDepartment of Pathology and Laboratory Medicine, University of Wisconsin - Madison, Wisconsin, USA.
Mark A RodgersDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-9800-3362
Abigail K GubernatDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Janelle L GleimDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Ryan V MoriartyDepartment of Pathology and Laboratory Medicine, University of Wisconsin - Madison, Wisconsin, USA.ORCID 0000-0001-7100-1906
Alexis J BalgemanDepartment of Pathology and Laboratory Medicine, University of Wisconsin - Madison, Wisconsin, USA.
Yonne T de MenezesDepartment of Immunobiology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.
Cassaundra L AmeelDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Daniel J FillmoreDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Skyler M PergalskeDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Jennifer A JunoDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-9072-1017
Pauline MaielloDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Harris B ChishtiDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Philana Ling LinDepartment of Pediatrics, UPMC's Children's Hospital of the University of Pittsburgh of UPMC, Pittsburgh, PA.
Dale I GodfreyDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Stephen J KentDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.ORCID 0000-0002-8539-4891
Daniel G PellicciDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.
Lishomwa C NdhlovuDepartment of Medicine, Division of Infectious Disease, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0001-5427-4187
Shelby L O'ConnorDepartment of Pathology and Laboratory Medicine, University of Wisconsin - Madison, Wisconsin, USA.ORCID 0000-0003-0183-5010
Charles A ScangaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
Practices CoreUC7AI180311 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI William Paul Duprex · 2023 to 2026
$13.2M
Effects of HIV SIV on unconventional T cells in immunity to M. tuberculosis in pre adolescentsR01AI142662 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NDHLOVU, LISHOMWA C, OCONNOR, SHELBY L · 2019 to 2023
$6.2M
Re-educating T cell-mediated immunity in SIV by modulating metabolic pathwaysK01OD033539 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LARSON, ERICA CHRISTINE · 2022 to 2024
$571k
NIAID NIH HHS R01 AI142662NIAID NIH HHS UC7 AI180311NIH HHS K01 OD033539NIH HHS P51 OD011106
6 · The paper itself

Abstract

Children living with HIV have a higher risk of developing tuberculosis (TB), a disease caused by the bacterium

Identifiers

PMID39091843
PMCPMC11291075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.