Evidence map›Paper›PMID 39091828›Full record

ArticlebioRxiv : the preprint server for biology2025

A tethering mechanism underlies Pin1-catalyzed proline

Christopher C Williams, Jonathan Chuck, Paola Munoz-Tello, Douglas J Kojetin

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Christopher C WilliamsSkaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, United States.ORCID 0000-0001-7503-0149
Jonathan ChuckSkaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, United States.
Paola Munoz-TelloDepartment of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States.
Douglas J KojetinDepartment of Integrative Structural and Computational Biology, Scripps Research and The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, Florida, United States.ORCID 0000-0001-8058-6168

Funding

Structural Biology of Multi-Domain Proteins and Multi-Protein Machinery in DNA Replication and RepairR35GM118089 · NIGMS · VANDERBILT UNIVERSITY · PI WALTER J. CHAZIN · 2016 to 2026
$4.9M
Acquisition of an 800 MHz NMRS10OD034276 · OD · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2024 to 2024
$2.0M
Mechanistic studies of corepressor-mediated PPARγ transcriptional repressionR01DK124870 · NIDDK · VANDERBILT UNIVERSITY · PI KOJETIN, DOUGLAS · 2020 to 2023
$1.9M
Bruker Avance III HD 600 MHz NMR spectrometerS10OD021550 · OD · SCRIPPS FLORIDA · PI KOJETIN, DOUGLAS · 2017 to 2017
$600k
Console upgrades for biological NMR spectrometersS10RR025677 · NCRR · VANDERBILT UNIVERSITY · PI SANDERS, CHARLES R · 2009 to 2009
$460k
Molecular mechanism of PIN1-mediated regulation of the nuclear receptor PPARyF31DK134167 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI WILLIAMS, CHRISTOPHER CONRAD · 2023 to 2025
$80k
NCRR NIH HHS S10 RR025677NIDDK NIH HHS F31 DK134167NIDDK NIH HHS R01 DK124870NIGMS NIH HHS R35 GM118089NIH HHS S10 OD021550NIH HHS S10 OD034276
6 · The paper itself

Abstract

The prolyl isomerase Pin1 catalyzes the

Indexed as

Biological SciencesBiophysics and Computational Biologycis-trans isomerizationenzymeNMR spectroscopynuclear receptorPin1PPARγproline isomerization

Identifiers

PMID39091828
PMCPMC11291072

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.