Evidence map›Paper›PMID 39091814›Full record

ArticlebioRxiv : the preprint server for biology2024

G-quadruplexes are a source of vulnerability in

Danielle L Keahi, Mathijs A Sanders, Matthew R Paul, Andrew L H Webster, Yin Fang, Tom F Wiley, Samer Shalaby, Thomas S Carroll, Settara C Chandrasekharappa, Carolina Sandoval-Garcia and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Danielle L KeahiLaboratory of Genome Maintenance, The Rockefeller University, New York, NY, USA.
Mathijs A SandersCancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.
Matthew R PaulBioinformatics Resource Center, The Rockefeller University, New York, NY, USA.
Andrew L H WebsterLaboratory of Genome Maintenance, The Rockefeller University, New York, NY, USA.
Yin FangLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY, USA.
Tom F WileyComparative Bioscience Center, The Rockefeller University, New York, NY, USA.
Samer ShalabyFlow Cytometry Resource Center, The Rockefeller University, New York, NY, USA.
Thomas S CarrollBioinformatics Resource Center, The Rockefeller University, New York, NY, USA.
Settara C ChandrasekharappaCancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Carolina Sandoval-GarciaDepartment of Neurosurgery, University of Minnesota, Minneapolis, MN, USA.
Margaret L MacMillanDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
John E WagnerDepartment of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
Mary E HattenLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-9059-660X
Agata SmogorzewskaLaboratory of Genome Maintenance, The Rockefeller University, New York, NY, USA.ORCID 0000-0001-6285-1562

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
Mechanisms of Cell Regulation and TransformationT32CA009673 · NCI · ROCKEFELLER UNIVERSITY · PI KAPOOR, TARUN M. · 1991 to 2018
$7.0M
Role of ASTN2 in Cerebellar Circuit Function and ASD-related BehaviorsR01NS116089 · NINDS · ROCKEFELLER UNIVERSITY · PI HATTEN, MARY ELIZABETH, HULL, COURT A · 2021 to 2025
$3.1M
Functions of human RAD51 and its paralogs during DNA interstrand crosslink repairR01CA204127 · NCI · ROCKEFELLER UNIVERSITY · PI SMOGORZEWSKA, AGATA · 2017 to 2021
$2.0M
NCATS NIH HHS UL1 TR001866NCI NIH HHS R01 CA204127NCI NIH HHS T32 CA009673NINDS NIH HHS R01 NS116089
6 · The paper itself

Abstract

Biallelic pathogenic variants in the essential DNA repair gene

Identifiers

PMID39091814
PMCPMC11291086

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.