Evidence map›Paper›PMID 39091779›Full record

ArticlebioRxiv : the preprint server for biology2024

Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain.

Wenbi Wu, Pankaj Kumar, Chad A Brautigam, Shih-Chia Tso, Hamid R Baniasadi, Daniel L Kober, Marie-Alda Gilles-Gonzalez

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Wenbi WuDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Pankaj KumarDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-7025-5530
Chad A BrautigamDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Shih-Chia TsoDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hamid R BaniasadiDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Daniel L KoberDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-8657-9348
Marie-Alda Gilles-GonzalezDepartment of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
Structural and mechanistic basis for the maturation of site-one protease in the secretory pathwayR01GM155152 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI Daniel Luke Kober · 2024 to 2026
$1.0M
The mechanistic basis for targeted protein degradation in lipid metabolismR00GM141261 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI KOBER, DANIEL LUKE · 2023 to 2025
$747k
NIGMS NIH HHS R00 GM141261NIGMS NIH HHS R01 GM155152NIGMS NIH HHS U24 GM129547
6 · The paper itself

Abstract

The heme-based direct oxygen sensor DosP degrades c-di-GMP, a second messenger nearly unique to bacteria. In stationary phase

Identifiers

PMID39091779
PMCPMC11291140

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.