Evidence map›Paper›PMID 39091770›Full record

ArticlebioRxiv : the preprint server for biology2024

Transcriptional, developmental, and functional parallels of lymphatic and venous smooth muscle.

Guillermo Arroyo-Ataz, Alejandra Carrasco Yagüe, Julia C Breda, Sarah A Mazzilli, Dennis Jones

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guillermo Arroyo-AtazDepartment of Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, 670 Albany Street, Boston, Massachusetts 02118, USA.
Alejandra Carrasco YagüeDepartment of Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, 670 Albany Street, Boston, Massachusetts 02118, USA.
Julia C BredaDepartment of Medicine, Division of Computational Biomedicine, Boston University Chobanian & Avedisian School of Medicine, 75 E. Newton Street, Boston, Massachusetts 02118, USA.
Sarah A MazzilliDepartment of Medicine, Division of Computational Biomedicine, Boston University Chobanian & Avedisian School of Medicine, 75 E. Newton Street, Boston, Massachusetts 02118, USA.
Dennis JonesDepartment of Pathology & Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, 670 Albany Street, Boston, Massachusetts 02118, USA.ORCID 0000-0002-1401-9701

Funding

Improving anti-tumor immunity in advanced breast cancer by targeting solid stressR01CA284133 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Dennis Jones · 2024 to 2026
$1.4M
Enhancing immunity by protecting lymphatic muscle cells from MRSA-Induced dysfunctionR01AR084505 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Dennis Jones · 2024 to 2026
$1.2M
NCI NIH HHS R01 CA284133NIAMS NIH HHS R01 AR084505
6 · The paper itself

Abstract

Lymphatic muscle cells (LMCs) are indispensable for lymphatic vessel contraction and their aberrant recruitment or absence is associated with both primary and secondary lymphedema. Despite their critical role in lymphatic vessel function, the transcriptomic and developmental basis that confer the unique contractile properties to LMCs are largely undefined. In this study, we employed single-cell RNA sequencing (scRNAseq), lineage tracing and

Identifiers

PMID39091770
PMCPMC11291064

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.