Evidence map›Paper›PMID 39091717›Full record

ArticleWorld journal of gastroenterology2024

GATIS score for predicting the prognosis of rectal neuroendocrine neoplasms: A Chinese multicenter study of 12-year experience.

Xin-Yu Zeng, Ming Zhong, Guo-Le Lin, Cheng-Guo Li, Wei-Zhong Jiang, Wei Zhang, Li-Jian Xia, Mao-Jun Di, Hong-Xue Wu, Xiao-Feng Liao and 6 more

Abstract readMulticenter Study
In one paragraph

Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Rectal neuroendocrine tumors: Update.World journal of gastrointestinal oncology · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Rectal neuroendocrine tumors: Can we predict their behavior?World journal of gastroenterology · 2025
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xin-Yu ZengDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, Hubei Province, China.
Ming ZhongDepartment of Gastrointestinal Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Guo-Le LinDepartment of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Beijing 100730, China.
Cheng-Guo LiDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, Hubei Province, China.
Wei-Zhong JiangDepartment of Colorectal Surgery, Fujian Medical University, Fuzhou 350401, Fujian Province, China.
Wei ZhangDepartment of Colorectal Surgery, Changhai Hospital, Shanghai 200433, China.
Li-Jian XiaDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Shandong First Medical University, Jinan 250118, Shandong Province, China.
Mao-Jun DiDepartment of Gastrointestinal Surgery, Taihe Hospital, Hubei University of Medicine, Shiyan 442099, Hubei Province, China.
Hong-Xue WuDepartment of Gastrointestinal Surgery I Section, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Xiao-Feng LiaoDepartment of General Surgery, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, Hubei Province, China.
Yue-Ming SunDepartment of Colorectal Surgery, Jiangsu Province Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.
Min-Hao YuDepartment of Gastrointestinal Surgery, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.
Kai-Xiong TaoDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, Hubei Province, China.
Yong LiDepartment of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, Guangdong Province, China.
Rui ZhangDepartment of Colorectal Surgery, Liaoning Cancer Hospital, Shenyang 110042, Liaoning Province, China.
Peng ZhangDepartment of Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430074, Hubei Province, China.zhangpengwh@hust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is currently a shortage of accurate, efficient, and precise predictive instruments for rectal neuroendocrine neoplasms (NENs).

aimTo develop a predictive model for individuals with rectal NENs (R-NENs) using data from a large cohort.

methodsData from patients with primary R-NENs were retrospectively collected from 17 large-scale referral medical centers in China. Random forest and Cox proportional hazard models were used to identify the risk factors for overall survival and progression-free survival, and two nomograms were constructed.

resultsA total of 1408 patients with R-NENs were included. Tumor grade, T stage, tumor size, age, and a prognostic nutritional index were important risk factors for prognosis. The GATIS score was calculated based on these five indicators. For overall survival prediction, the respective C-indexes in the training set were 0.915 (95% confidence interval: 0.866-0.964) for overall survival prediction and 0.908 (95% confidence interval: 0.872-0.944) for progression-free survival prediction. According to decision curve analysis, net benefit of the GATIS score was higher than that of a single factor. The time-dependent area under the receiver operating characteristic curve showed that the predictive power of the GATIS score was higher than that of the TNM stage and pathological grade at all time periods.

conclusionThe GATIS score had a good predictive effect on the prognosis of patients with R-NENs, with efficacy superior to that of the World Health Organization grade and TNM stage.

Indexed as

Neoplasm StagingNeuroendocrine TumorsNomogramsRectal NeoplasmsAdultAgedChinaEast Asian PeopleFemaleHumansMaleMiddle AgedNeoplasm GradingNutrition AssessmentPredictive Value of TestsPrognosisNomogramOverall survivalPrognosisProgression-free survivalRandom forestRectal neuroendocrine neoplasm

Identifiers

PMID39091717
PMCPMC11290398

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.