Evidence map›Paper›PMID 39091690›Full record

ArticleJAC-antimicrobial resistance2024

Antimicrobial prescribing in referral hospitals in Timor-Leste: results of the first two national point prevalence surveys, 2020-21.

Guilherme Ximenes, Sajal K Saha, Helio Guterres, Adriano Vieira, Lisa Harris, Michelle Mahony, Agata Dos Santos, Lucia Toto, Elfiana Amaral, Jessie C Spargo and 7 more

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Guilherme XimenesMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Sajal K SahaMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Helio GuterresDepartment of Internal Medicine, Hospital Nacional Guido Valadares, Dili, Timor-Leste.
Adriano VieiraMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Lisa HarrisMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Michelle MahonyMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Agata Dos SantosPharmacy Department, Hospital Nacional Guido Valadares, Dili, Timor-Leste.
Lucia TotoMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Elfiana AmaralMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Jessie C SpargoDepartment of Paediatrics, Royal Darwin Hospital, Darwin 0810, Northern Territory, Australia.
Sze Yen TayMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Salvador AmaralMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Karen ChamplinMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Anthony D K DraperMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Joshua R FrancisMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Jennifer YanMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.
Sarah A LynarMenzies School of Health Research, Charles Darwin University, Dili, Timor-Leste.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To describe antimicrobial use (AMU) in patients admitted to hospitals in Timor-Leste. Methods: In 2020 and 2021, we undertook antimicrobial prescribing point prevalence surveys across all six hospitals in Timor-Leste (one national and five municipal) to describe AMU and appropriateness in admitted patients. Results: In 2020, 291/394 (73.9%) surveyed patients had been prescribed antimicrobials, compared with 260/403 (64.5%) in 2021 ( Conclusions: Most patients admitted to hospital in Timor-Leste are prescribed antimicrobials, and approximately one-third of these prescriptions are inappropriate. However, this was in the context of limited local guideline availability at the time of surveys and limited microbiological culture capacity outside of the capital, Dili. Improved microbiological guidance, iterative guideline revisions based on local antimicrobial resistance (AMR) surveillance data, and enhanced stewardship activities including further point prevalence studies, could improve antimicrobial use, optimize patient outcomes and reduce AMR in Timor-Leste.

Identifiers

PMID39091690
PMCPMC11293431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.