Evidence map›Paper›PMID 39091604›Full record

ReviewTherapeutic advances in medical oncology2024

Research progress and future directions of immune checkpoint inhibitor combination therapy in advanced gastric cancer.

Puyi He, Long Ma, Bo Xu, Yunpeng Wang, Xiaomei Li, Hao Chen, Yumin Li

Abstract readReview
In one paragraph

Review in Therapeutic advances in medical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Progress of immune checkpoint inhibitors in gastric cancer.World journal of gastrointestinal oncology · 2025
    Review
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Puyi HeThe Second Hospital of Lanzhou University, Lanzhou, China.
Long MaThe Second Hospital of Lanzhou University, Lanzhou, China.
Bo XuThe Second Hospital of Lanzhou University, Lanzhou, China.
Yunpeng WangThe Second Hospital of Lanzhou University, Lanzhou, China.
Xiaomei LiThe Second Hospital of Lanzhou University, Lanzhou, China.
Hao ChenThe Second Hospital of Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0003-0018-480X
Yumin LiThe Second Hospital of Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0000-0002-4101-2134

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, with the continuous development of molecular immunology, immune checkpoint inhibitors (ICIs) have also been widely used in the treatment of gastric cancer, but they still face some challenges: The first is that only some people can benefit, the second is the treatment-related adverse events (TRAEs) that occur during treatment, and the third is the emergence of varying degrees of drug resistance with long-term use. How to overcome these challenges, combined therapy based on ICIs has become one of the important strategies. This article summarizes the clinical application of ICIs combined with chemotherapy, targeted therapy, radiotherapy, photodynamic therapy, thermotherapy, immune adjuvant, and dual immunotherapy and discusses the mechanism, and also summarizes the advantages and disadvantages of the current combination modalities and the potential research value. The aim of this study is to provide more and more optimized combination regimen for ICI combined therapy in patients with advanced gastric cancer and to provide reference for clinical and scientific research.

Indexed as

chemotherapycombination therapyimmune checkpoint inhibitorsimmunological adjuvantphysical therapytargeted therapy

Identifiers

PMID39091604
PMCPMC11292724

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.