Evidence map›Paper›PMID 39091441›Full record

ArticleJournal of human reproductive sciences

Elevated Levels of Gonadotrophic Hormones and Antioxidant Biomarker in Male Rats Following Administration of Hydromethanol Leaf Extract of

Samuel Kelechi Mobisson, Uchechukwu Loveth Iyanyi, Ben Enoluomen Ehigiator, Fidelis U Ibe, Justin Bonaparte Monye, Agona O Obembe

Abstract read
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In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samuel Kelechi MobissonDepartment of Human Physiology, Faculty of Basic Medical Sciences, Madonna University, Elele, Rivers, Nigeria.
Uchechukwu Loveth IyanyiDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Madonna University, Elele, Rivers, Nigeria.
Ben Enoluomen EhigiatorDepartment of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Edo State University, Uzairue, Nigeria.
Fidelis U IbeDepartment of Human Physiology, Faculty of Basic Medical Sciences, Madonna University, Elele, Rivers, Nigeria.
Justin Bonaparte MonyeDepartment of Human Physiology, Faculty of Basic Medical Sciences, Madonna University, Elele, Rivers, Nigeria.
Agona O ObembeDepartment of Human Physiology, Faculty of Basic Medical Sciences, University of Calabar, Cross River, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: 2,4-Dinitrophenylhydrazine induces testicular toxicity and can result in reproductive dysfunction in male rats. Aim: This study investigated the effects of hydromethanolic leaf extract of Settings and Design: Twenty rats (90-170 g) were grouped into five (A-E) ( Materials and Methods: Group A (control) received 0.5 mL of normal saline, Groups B to E received PHZ, PHZ + Astymin (0.5 mL), PHZ + Statistical Analysis Used: The data were analysed using a one-way analysis of variance and the Bonferroni Results: Follicle-stimulating hormone (FSH) decreased significantly in PHZ, PHZ + Astymin and PHZ + Conclusion: PHZ administration caused testicular toxicity and altered biochemical markers, astymin treatment reduced male reproductive hormones, while

Indexed as

AstyminJusticia secundaphenylhydrazinetestosterone

Identifiers

PMID39091441
PMCPMC11290714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.