ReviewFrontiers in cardiovascular medicine2024
Value of the triglyceride-glucose index and related parameters in heart failure patients.
Review in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The Triglyceride-Glucose Index: A Novel Marker for Clinical Atherosclerotic Cardiovascular Disease Risk Stratification.Annals of African medicine · 2026Review
- Association between TyG-related indices and in-hospital acute heart failure in patients with acute myocardial infarction after emergency percutaneous coronary intervention.Frontiers in endocrinology · 2026Article
- Relationship between C-reactive protein triglyceride glucose index and cardiovascular disease risk: a cross-sectional analysis with machine learning.BMC medical informatics and decision making · 2025Article
- Effect of a digital health intervention on outpatients with heart failure: a randomized, controlled trial.European heart journal. Digital health · 2025Article
- The Triglyceride-Glucose Index, a Marker of Insulin Resistance, Is Associated with the Myocardial Performance Index in Asymptomatic Subjects.Medicina (Kaunas, Lithuania) · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The triglyceride-glucose (TyG) index, proven to be a crucial insulin resistance biomarker (better than the Homeostasis Model Assessment for Insulin Resistance), is simple and non-invasive. Recently, indisputable evidence has shown that the TyG index is strongly associated with cardiovascular disease [CVD, including atherosclerosis, heart failure (HF), and hypertension] prognosis and mortality. Nevertheless, the value of the TyG index in HF patients treated with sodium-glucose cotransporter 2 inhibitors (SGLT2is) has not been systematically evaluated. Therefore, in this review, we summarized the value of the TyG index and its related parameters as markers of CVD, especially HF. Furthermore, we addressed the use of SGLT2is and GLP-1 receptor antagonists in HF patients. Finally, we summarized the mechanism of the "obesity paradox."
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Registered trials
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