Evidence map›Paper›PMID 39091305›Full record

ArticleFrontiers in microbiology2024

Surveillance of Erythrovirus B19 (B19V) in patients with acute febrile illness suspected of arboviruses in Mato Grosso do Sul state, Brazil.

Gislene Garcia C Lichs, Zoraida Del Carmen Fernandez, Valdinete Alves do Nascimento, Daniel Maximo Corrêa Alcantara, Everton Ferreira Lemos, Cristiano M Espínola Carvalho, Luiz Henrique Ferraz Demarchi, Crhistinne Carvalho Maymone Gonçalves, Felipe Gomes Naveca, Alexsandra Rodrigues de Mendonça Favacho

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gislene Garcia C LichsLaboratório Central de Saúde Pública de Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Zoraida Del Carmen FernandezFundação Oswaldo Cruz, Fiocruz Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Valdinete Alves do NascimentoNúcleo de Vigilância de Vírus Emergentes, Reemergentes ou Negligenciados, Instituto Leônidas e Maria Deane, Fiocruz, Manaus, Amazonas, Brazil.
Daniel Maximo Corrêa AlcantaraFundação Oswaldo Cruz, Fiocruz Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Everton Ferreira LemosUniversidade Estadual de Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Cristiano M Espínola CarvalhoUniversidade Católica Dom Bosco, Campo Grande, Mato Grosso do Sul, Brazil.
Luiz Henrique Ferraz DemarchiLaboratório Central de Saúde Pública de Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Crhistinne Carvalho Maymone GonçalvesPostgraduate Program in Infectious and Parasitic Diseases, Universidade Federal de Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.
Felipe Gomes NavecaNúcleo de Vigilância de Vírus Emergentes, Reemergentes ou Negligenciados, Instituto Leônidas e Maria Deane, Fiocruz, Manaus, Amazonas, Brazil.
Alexsandra Rodrigues de Mendonça FavachoPostgraduate Program in Infectious and Parasitic Diseases, Universidade Federal de Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Human Erythrovirus (parvovirus) B19 infection can produce symptoms similar to those produced by Dengue, Chikungunya, and Zika viruses, making clinical diagnosis difficult. The importance of erythrovirus B19 in human pathology has been increased and reported in numerous studies published globally. Methods: The B19V infection was investigated by real-time PCR in sera samples from patients with signs and symptoms related to classic arboviral symptoms. This study was conducted to provide information on the genetic diversity of Human Erythrovirus B19 (B19V) circulating in the state of Mato Grosso do Sul, Midwest region of Brazil, from 2017 to 2022. A total of 773 sera samples of patients with negative diagnostic results for Dengue, Chikungunya, and Zika, during the study period were analyzed. Results: Erythrovirus DNA was found in 10.6% (82/773) of patients, among them 10 were pregnant women. Four samples were completely sequenced, and the other five partially, to genotype by phylogenetic reconstruction. All samples belong to worldwide dispersed genotype 1, subgenotype 1a. Discussion: The findings of the study demonstrate the importance of including B19V in differential laboratory diagnosis for epidemiological purposes and appropriate patient management. The diagnosis for B19V should be performed, particularly among pregnant women, immunocompromised patients, and individuals with hemolytic diseases, given that the infection is more severe in these cases.

Indexed as

ChikungunyaDenguedifferential diagnosishumanParvovirus B19surveillanceZika

Identifiers

PMID39091305
PMCPMC11291312

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.