ArticleSmall methods2024
Selective Segregation of Thermo-Responsive Microgels via Microfluidic Technology.
Article in Small methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Particle-Based Detection of Surface Chemistry via Optical Microscopy-Integrating Microfluidics, Light-Induced Activity of Colloids and Data Science.Small methods · 2026Article
- Surface-Sensitive Fractioning of Flowing Colloidal Suspensions Sedimented at a Photochemically Active Wall.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Selective Segregation of Thermo-Responsive Microgels via Microfluidic Technology.Small methods · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Separation of equally sized particles distinguished solely by material properties remains still a very challenging task. Here a simple separation of differently charged, thermo-responsive polymeric particles (for example microgels) but equal in size, via the combination of pressure-driven microfluidic flow and precise temperature control is proposed. The separation principle relies on forcing thermo-responsive microgels to undergo the volume phase transition during heating and therefore changing its size and correspondingly the change in drift along a pressure driven shear flow. Different thermo-responsive particle types such as different grades of ionizable groups inside the polymer matrix have different temperature regions of volume phase transition temperature (VPTT). This enables selective control of collapsed versus swollen microgels, and accordingly, this physical principle provides a simple method for fractioning a binary mixture with at least one thermo-responsive particle, which is achieved by elution times in the sense of particle chromatography. The concepts are visualized in experimental studies, with an intend to improve the purification strategy of the broad distribution of charged microgels into fractioning to more narrow distribution microgels distinguished solely by slight differences in net charge.
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Registered trials
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