Evidence map›Paper›PMID 39091044›Full record

ArticleESC heart failure2024

Wearable defibrillator to improve accuracy in selecting candidates to implantable defibrillator: A real-world experience.

Gabriele Dell'Era, Philippe Caimmi, Enrico Guido Spinoni, Eleonora Battistini, Stefano Porcellini, Federica De Vecchi, Matteo Santagostino, Chiara Ghiglieno, Anna Degiovanni, Fabrizio Leigheb and 3 more

Abstract read
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gabriele Dell'EraCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.ORCID 0000-0002-7517-0771
Philippe CaimmiMaggiore della Carità Hospital of Novara, Novara, Italy.
Enrico Guido SpinoniCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.
Eleonora BattistiniCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.
Stefano PorcelliniCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.
Federica De VecchiCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.
Matteo SantagostinoCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.
Chiara GhiglienoDepartment of Cardiology, University of Eastern Piedmont, Novara, Italy.
Anna DegiovanniCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.
Fabrizio LeighebMaggiore della Carità Hospital of Novara, Novara, Italy.
Daniela KozelMaggiore della Carità Hospital of Novara, Novara, Italy.
Andrea CapponiMaggiore della Carità Hospital of Novara, Novara, Italy.
Giuseppe PattiCardiology Unit, Maggiore della Carità Hospital of Novara, Novara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe indication for implantable cardioverter defibrillator (ICD) for sudden cardiac death (SCD) prevention relies mostly on left ventricular ejection fraction (LVEF) ≤ 35%. The use of a wearable cardioverter defibrillator (WCD) in the case of dynamic alterations of LVEF may help avoid an improper early ICD implant when a favourable evolution in the post-acute phase is observed and may help reduce costs.

methodsThis parallel cohort retrospective study included patients with heart failure with reduced ejection fraction (HFrEF) at high risk of arrhythmias recruited in the acute phase and divided into an early ICD cohort and a WCD cohort for primary prevention during the waiting period established by European Society of Cardiology guidelines.

resultsA total of 41 consecutive patients were enrolled: 26 in the WCD group and 15 in the early ICD group. Age, LVEF at baseline, causes of HFrEF and drug therapy in the two cohorts were similar. During the waiting period after the inclusion, three patients (11.5%) in the WCD cohort and four (26.7%) in the early ICD cohort developed relevant ventricular arrhythmias (P = 0.22); none of them had subsequent LVEF recovery. At the end of the waiting period, 13 patients (50%) in the WCD group and 7 (46.7%) in the early ICD group experienced LVEF recovery (P = 0.84). The average cost per patient at the end of the waiting period was €23 934 in the early ICD cohort versus €19 167 in the WCD cohort (-19.9%). This cost savings from WCD use appears even higher when projected over a 10 year period (-41.2%).

conclusionsWCD may represent a cost-effective strategy to more accurately select candidates for the primary prevention ICD implant among high-risk patients with HFrEF. ICD use provides effective protection from SCD and reduces costs compared with an extensive early ICD implant.

Indexed as

Death, Sudden, CardiacDefibrillators, ImplantableHeart FailurePatient SelectionStroke VolumeWearable Electronic DevicesAgedDefibrillatorsFemaleFollow-Up StudiesHumansMaleMiddle AgedPrimary PreventionRetrospective StudiesVentricular Function, Leftarrhythmiasheart failuresudden deathwearable electronic devices

Identifiers

PMID39091044
PMCPMC11631226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.