Evidence map›Paper›PMID 39090965›Full record

ArticleScience progress

The effects of a diet with high fat content from lard on the health and adipose-markers' mRNA expression in mice.

Dinh-Toi Chu, Hue Vu Thi, Nhat-Le Bui, Ngoc-Hoan Le

Abstract read
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dinh-Toi ChuCenter for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam.ORCID 0000-0002-4596-2022
Hue Vu ThiCenter for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam.
Nhat-Le BuiCenter for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam.
Ngoc-Hoan LeFaculty of Biology, Hanoi National University of Education, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pork is one type of the most frequently consumed meat with about 30% globally. Thus, the questions regarding to the health effects of diet with high fat content from lard are raised. Here, we developed a model of mice fed with high fat (HF) from lard to investigate and have more insights on the effects of long-time feeding with HF on health. The results showed that 66 days on HF induced a significant gain in the body weight of mice, and this weight gain was associated to the deposits in the white fat, but not brown fat. The glucose tolerance, not insulin resistance, in mice was decreased by the HF diet, and this was accompanied with significantly higher blood levels of total cholesterol and triglycerides. Furthermore, the weight gains in mice fed with HF seemed to link to increased mRNA levels of adipose biomarkers in lipogenesis, including

Indexed as

BiomarkersDietary FatsDiet, High-FatRNA, MessengerAdipose TissueAdipose Tissue, WhiteAnimalsBody WeightInsulin ResistanceMaleMiceMice, Inbred C57BLTriglyceridesWeight GainBiomarkersDietary FatslardRNA, MessengerTriglyceridesadipose-markersblood dyslipidemiaglucose toleranceHigh fat dietlardmRNA expressionweight gainswhite fat

Identifiers

PMID39090965
PMCPMC11297511

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.