Evidence map›Paper›PMID 39090732›Full record

Observational studyJournal of cardiothoracic surgery2024

Association of postoperative delirium with hypotension in critically ill patients after cardiac surgery: a prospective observational study.

Saleh Mohammed Alhaj Othman, Mohammed Ali Ali Aziz, Gaber Musaed Ali Al-Mushiki, Chanyanud Sriwayyapram, Tecleab Okubai, Gamil Al-Muwaffaq, Qin Xu, Mohammed Alqudaimi

Abstract readObservational Study
In one paragraph

Observational study in Journal of cardiothoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saleh Mohammed Alhaj OthmanNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.
Mohammed Ali Ali AzizNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.
Gaber Musaed Ali Al-MushikiNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.
Chanyanud SriwayyapramNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.
Tecleab OkubaiNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.
Gamil Al-MuwaffaqNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.
Qin XuNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China. qinxu@njmu.edu.cn.
Mohammed AlqudaimiNanjing Medical University, Longmian Avenue No.101, Jiangning District, Nanjing, Jiangsu, China.

Funding

Priority Discipline Development Program of Jiangsu Higher Education Institutions (General Office, the People Government of Jiangsu Province ) 2018 No.87
6 · The paper itself

Abstract

backgroundPostoperative delirium (POD), an acute and variable disturbance in cognitive function, is an intricate and elusive phenomenon that occurs after cardiac surgery. Despite progress in surgical techniques and perioperative management, POD remains a formidable challenge, imposing a significant burden on patients, caregivers, and healthcare systems.

methodsThis prospective observational study involved 307 patients who underwent cardiac surgery. Data on the occurrence of delirium, clinical parameters, and postoperative characteristics were collected. A multivariate analysis was performed to assess the relationship between POH and POD.

resultsSixty-one patients (21%) developed delirium, with an average onset of approximately 5 days postoperatively and a duration of approximately 6 days. On multivariate analysis, POH was significantly associated with POD, and the adjusted odds ratios indicated that patients with POH were more likely to develop delirium (OR, 5.61; p = 0.006). Advanced age (OR, 1.11; p = 0.002), emergency surgery (OR, 8.31; p = 0.001), and on-pump coronary artery bypass grafting were identified as risk factors of POD. Patients who developed delirium were typically older, more likely to be male, and had higher morbidity rates than those who did not.

conclusionPOH is significantly associated with delirium in critically ill patients after cardiac surgery. Surgical complexity and advanced age contribute to the risk of developing POD and poor postoperative outcomes.

Indexed as

Cardiac Surgical ProceduresCritical IllnessDeliriumHypotensionPostoperative ComplicationsAgedFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsAdult populationCritical illnessDeliriumOpen heart surgeryPostoperative carePostoperative hypotensionSurgery-related complications

Identifiers

PMID39090732
PMCPMC11293154

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.