Evidence map›Paper›PMID 39090582›Full record

ArticleBMC urology2024

A model of tertiary lymphatic structure-related prognosis for penile squamous cell carcinoma.

Han Tang, Zhengwei Su, Qingming Huang, Yongpeng Li, Rongchao Chen, Chengjie Ban, Chanzhen Liu, Haoyuan Lu, Xian-Lin Yi, Yong Tang

Abstract read
In one paragraph

Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Han Tang *Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Zhengwei Su *Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Qingming Huang *Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Yongpeng LiDepartment of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Rongchao ChenDepartment of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Chengjie BanDepartment of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Chanzhen LiuDepartment of Gynecology and Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Haoyuan LuDepartment of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China.
Xian-Lin YiDepartment of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China. yzztx@126.com.
Yong TangDepartment of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, China. yong_tang_md@hotmail.com.

Funding

The National Natural Science Fund of China 32260241
6 · The paper itself

Abstract

backgroundWe investigated the feasibility of the tertiary lymphoid structure (TLS) as a prognostic marker for penile squamous cell carcinoma(SCC).

methodsWe retrospectively collected data from 83 patients with penile squamous cell carcinoma. H&E-stained slides were reviewed for TLS density. In addition, clinical parameters were analyzed, the prognostic value of these parameters on overall survival (OS) was evaluated using ‒ Kaplan-Meier survival curves, and the prognostic value of influencing factors was evaluated using Cox multifactor design nomogram analysis.

resultBMI, T, N, and M are significant in the survival curve with or without tertiary lymphoid structure. BMI, T, N, M and TLS were used to construct a prognostic model for penile squamous cell carcinoma, and the prediction accuracy reached a consensus of 0.884(0.835-0.932), and the decision consensus reached 0.581(0.508-0.655).

conclusionTLS may be a positive prognostic factor for penile squamous cell carcinoma, and the combination of BMI, T, N and M can better evaluate the prognosis of patients.

Indexed as

Carcinoma, Squamous CellPenile NeoplasmsTertiary Lymphoid StructuresAdultAgedHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival RateImmunityLymphocytesPenile squamous cell carcinomaTertiary lymphoid structure

Identifiers

PMID39090582
PMCPMC11295339

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