Evidence map›Paper›PMID 39090518›Full record

ArticleInternational urology and nephrology2025

The modified 5-item frailty index as a predictor of perioperative risk in patients undergoing percutaneous nephrolithotomy.

Kays Chaker, Yassine Ouanes, Mahdi Marrak, Nader Gharbia, Moez Rahoui, Boutheina Mosbahi, Mokhtar Bibi, Wassim Ben Chedly, Yassine Nouira

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In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kays ChakerUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia. chakerkays@gmail.com.ORCID http://orcid.org/0000-0003-0193-3972
Yassine OuanesUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.
Mahdi MarrakUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.
Nader GharbiaUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.
Moez RahouiUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.
Boutheina MosbahiAnesthesiology Department, LA RABTA Hospital, University of Tunis El Manar, Tunis, Tunisia.
Mokhtar BibiUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.
Wassim Ben ChedlyUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.
Yassine NouiraUrology Department, LA RABTA Hospital, University of Tunis El Manar, Bab Saadoun, 1006, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe modified 5-item frailty index is a relatively new tool to assess the post-operative complication risks. In urology, there is limited literature on the impact of frailty on percutaneous nephrolithotomy (PCNL) outcomes. We aimed to compare the predictive value of the modified 5-item frailty index (mFI-5) to identify high risk patients prior to PCNL.

methodsA database of patients undergoing PCNL, between 2015 and 2022, was analyzed. Patient frailty was assessed using the mFI-5 index. The mFI-5 index was calculated based on the presence of the five co-morbidities: congestive heart failure within 30 days prior to surgery, diabetes mellitus, chronic obstructive pulmonary disease, partially dependent or totally dependent functional health status at time of surgery, and hypertension requiring medication. Patients were grouped as not frail (mFI-5 = 0), intermediate (mFI-5 = 1), and severely frail (mFI-5 ≥ 2). Primary outcomes were 30-day postoperative complications. Secondary outcomes were hospitalization: total hospital length of stay, reoperation, and unplanned readmission.

resultsFrom a total of 320 PCNL patients included for analysis, 54.06% (n = 173) were not frail, 17.81% (n = 57) were intermediate, and 28.12% (n = 90) were severely frail. Frail patients were likely to be older (p = 0.002) and have a higher American Society of Anesthesiologists score (p = 0.001), chronic kidney disease (p < 0.001). Patients of intermediate or severe frailty were more likely to exhibit postoperative sepsis (p = 0.042), significant blood loss (p = 0.036) and require intensive care units admissions (p = 0.0015). Frail patients had a longer hospital length of stay (p < 0.001) and tended to require reoperation (p = 0.001), and unplanned readmission (p = 0.02).

conclusionFrailty assessment appears useful in stratifying those at risk of extended hospitalization, septic and hemorrhagic complications, readmission, or reoperation after PCNL. Preoperative assessment of frailty phenotype may give insight into treatment decisions and assist surgeons in counselling patients on expected course and hospital stay following PCNL.

Indexed as

FrailtyNephrolithotomy, PercutaneousPostoperative ComplicationsAgedFemaleHumansLength of StayMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentComplicationsFrailtyPercutaneous nephrolithotomyStone

Identifiers

PMID39090518
PMCPMC11695494

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.