Evidence map›Paper›PMID 39090465›Full record

ArticleBulletin of experimental biology and medicine2024

GDF11 (Protein of Juvenility) and GDF15 (Protein of Senility) in the Plasma of Patients with Sleep Apnea Syndrome: a Pilot Study.

I M Madaeva, E V Titova, O N Berdina, L F Sholokhov, N V Semenova, S I Kolesnikov, L I Kolesnikova

Abstract read
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Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

I M MadaevaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia. nightchild@mail.ru.
E V TitovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
O N BerdinaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L F SholokhovScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
N V SemenovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
S I KolesnikovScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L I KolesnikovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a matched-pair analysis of the content of GDF11 and GDF15 proteins in the plasma of patients (56 middle-aged men) with obstructive sleep apnea syndrome (OSAS) and healthy volunteers (27 men with no complaints of sleep disorders). The groups were comparable in terms of age and presence of chronic diseases. No statistically significant differences in GDF11 content in the studied groups were revealed, while the content of GDF15 in the OSAS group was 1.3 times higher. These results require further research from the viewpoint of geriatric somnology and molecular biology.

Indexed as

Bone Morphogenetic ProteinsGrowth Differentiation Factor 15Growth Differentiation FactorsSleep Apnea, ObstructiveAdultAgedBone Morphogenetic Protein 15Case-Control StudiesHumansMaleMiddle AgedPilot ProjectsSleep Apnea SyndromesBone Morphogenetic Protein 15Bone Morphogenetic ProteinsGDF11 protein, humanGDF15 protein, humanGrowth Differentiation Factor 15Growth Differentiation Factorsapnea syndromeGDF11GDF15intermittent nocturnal hypoxiasleep structure

Identifiers

PMID39090465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.