Evidence map›Paper›PMID 39090333›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2024

(-)-Carvone Inhibits Oxytocin-induced Writhing Via Uterine Relaxation in Rodents.

Olivaneide da Silva Frazão, Mariana Coelho Brito, Cícero André Ferreira Macêdo, Tiago Feitosa Ribeiro, Jennifer Milene Gomes França, Bárbara Artimis Gonçalves Carvalho, Diego Barbosa de Queiroz, Pedro Modesto Nascimento Menezes, Fernanda Pires de Almeida Ribeiro, Fabrício Souza Silva

Abstract read
PubMed Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Olivaneide da Silva FrazãoPostgraduate Program in Biosciences, Federal University of San Francisco Valley (UNIVASF), Petrolina, Pernambuco, Brazil.
Mariana Coelho BritoLaboratory of Experimental Pharmacology, College of Pharmacy - Federal University of San Francisco Valley (UNIVASF), Av. José de Maniçoba S/N, Centro, Petrolina, PE, CEP: 56304-917, Brazil.
Cícero André Ferreira MacêdoLaboratory of Experimental Pharmacology, College of Pharmacy - Federal University of San Francisco Valley (UNIVASF), Av. José de Maniçoba S/N, Centro, Petrolina, PE, CEP: 56304-917, Brazil.
Tiago Feitosa RibeiroNortheast Biotechnology Network, Federal Rural University of Pernambuco (UFRPE), Recife, Pernambuco, Brazil.
Jennifer Milene Gomes FrançaLaboratory of Experimental Pharmacology, College of Pharmacy - Federal University of San Francisco Valley (UNIVASF), Av. José de Maniçoba S/N, Centro, Petrolina, PE, CEP: 56304-917, Brazil.
Bárbara Artimis Gonçalves CarvalhoLaboratory of Experimental Pharmacology, College of Pharmacy - Federal University of San Francisco Valley (UNIVASF), Av. José de Maniçoba S/N, Centro, Petrolina, PE, CEP: 56304-917, Brazil.
Diego Barbosa de QueirozUniversity of Pernambuco, Campus Petrolina, Brazil.
Pedro Modesto Nascimento MenezesLaboratory of Experimental Pharmacology, College of Pharmacy - Federal University of San Francisco Valley (UNIVASF), Av. José de Maniçoba S/N, Centro, Petrolina, PE, CEP: 56304-917, Brazil.
Fernanda Pires de Almeida RibeiroLaboratory of Experimental Pharmacology, College of Pharmacy - Federal University of San Francisco Valley (UNIVASF), Av. José de Maniçoba S/N, Centro, Petrolina, PE, CEP: 56304-917, Brazil.
Fabrício Souza SilvaPostgraduate Program in Biosciences, Federal University of San Francisco Valley (UNIVASF), Petrolina, Pernambuco, Brazil. fabricio.souzasilva@univasf.edu.br.ORCID 0000-0002-6394-6501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(-)-Carvone, a ketone monoterpene, is the main component of essential oils from several medicinal plants and has been reported to have anti-arthriric, anticonvulsive, antidiabetic, anti-inflammatory, anticancer, and immunomodulatory effects. Therefore, this study aimed to investigate the spasmolytic activity of (-)-carvone in rodent models. The isolated virgin rat uterus was mounted in an organ bath apparatus, and the relaxing effect of ( -)-carvone and its mechanism of action were evaluated in tonic contractions induced by carbachol, KCl, PGF

Indexed as

Cyclohexane MonoterpenesMonoterpenesOxytocinUterusAnimalsCarbacholFemaleMiceMuscle RelaxationParasympatholyticsRatsRats, WistarUterine ContractionCarbacholcarvoneCyclohexane MonoterpenesMonoterpenesOxytocinParasympatholyticsAcute toxicityMonoterpenePrimary dysmenorrheaRat uterusSmooth muscle

Identifiers

PMID39090333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.