Evidence map›Paper›PMID 39090285›Full record

ArticleJournal of exposure science & environmental epidemiology2025

A data-driven approach to identifying PFAS water sampling priorities in Colorado, United States.

Kelsey E Barton, Peter J Anthamatten, John L Adgate, Lisa M McKenzie, Anne P Starling, Kevin Berg, Robert C Murphy, Kristy Richardson

Abstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelsey E BartonToxicology and Environmental Epidemiology Office, Colorado Department of Public Health & Environment, Denver, CO, USA. Kelsey.Barton@state.co.us.ORCID http://orcid.org/0000-0001-6103-8975
Peter J AnthamattenDepartment of Geography and Environmental Science, University of Colorado Denver, Denver, CO, USA.
John L AdgateDepartment of Environmental & Occupational Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Lisa M McKenzieDepartment of Environmental & Occupational Health, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Anne P StarlingDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Kevin BergToxicology and Environmental Epidemiology Office, Colorado Department of Public Health & Environment, Denver, CO, USA.
Robert C MurphySource Water Assessment & Protection Program, Colorado Department of Public Health & Environment, Denver, CO, USA.
Kristy RichardsonToxicology and Environmental Epidemiology Office, Colorado Department of Public Health & Environment, Denver, CO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPer and polyfluoroalkyl substances (PFAS), a class of environmentally and biologically persistent chemicals, have been used across many industries since the middle of the 20

objectiveOur objective was to incorporate known and potential PFAS sources, physical characteristics of the environment, and existing PFAS water sampling results into a PFAS risk prediction map that may be used to develop a PFAS water sampling prioritization plan for the Colorado Department of Public Health and Environment (CDPHE).

methodsWe used random forest classification to develop a predictive surface of potential groundwater contamination from two PFAS, perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA). The model predicted PFAS risk at locations without sampling data into one of three risk categories after being "trained" with existing PFAS water sampling data. We used prediction results, variable importance ranking, and population characteristics to develop recommendations for sampling prioritization.

resultsSensitivity and precision ranged from 58% to 90% in the final models, depending on the risk category. The model and prioritization approach identified private wells in specific census blocks, as well as schools, mobile home parks, and public water systems that rely on groundwater as priority sampling locations. We also identified data gaps including areas of the state with limited sampling and potential source types that need further investigation. IMPACT STATEMENT: This work uses random forest classification to predict the risk of groundwater contamination from two per- and polyfluoroalkyl substances (PFAS) across the state of Colorado, United States. We developed the prediction model using data on known and potential PFAS sources and physical characteristics of the environment, and "trained" the model using existing PFAS water sampling results. This data-driven approach identifies opportunities for PFAS water sampling prioritization as well as information gaps that, if filled, could improve model predictions. This work provides decision-makers information to effectively use limited resources towards protection of populations most susceptible to the impacts of PFAS exposure.

Indexed as

Alkanesulfonic AcidsCaprylatesEnvironmental MonitoringFluorocarbonsGroundwaterWater Pollutants, ChemicalColoradoHumansRisk AssessmentAlkanesulfonic AcidsCaprylatesFluorocarbonsperfluorooctane sulfonic acidperfluorooctanoic acidWater Pollutants, ChemicalEmerging contaminantsEnvironmental monitoringGeospatial analysesPerfluorinated chemicalsVulnerable populations

Identifiers

PMID39090285
PMCPMC12069103

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.