Evidence map›Paper›PMID 39090126›Full record

ArticleNature communications2024

Sequence-specific nanoparticle barcode strategy for multiplex human enterovirus typing.

Zecheng Zhong, Xiaosong Su, Kunyu Yang, Weida Huang, Jin Wang, Zhihao Zhuo, Jiyu Xiang, Lesi Lin, Shuizhen He, Tingdong Li and 4 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Enzymatic DNA Reaction Networks for Orchestrating Stimuli-Dependent Temporal Molecular Pulse.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zecheng Zhong *State Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Xiaosong Su *Zhongshan Hospital Fudan University Xiamen Branch, Xiamen, 361015, Fujian, China.
Kunyu Yang *State Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Weida HuangState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Jin WangState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Zhihao ZhuoState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Jiyu XiangState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Lesi LinState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.
Shuizhen HeXiamen Haicang Hospital, Haiyu Road, Xiamen, 361026, Fujian, China.
Tingdong LiState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.ORCID 0000-0003-0685-2549
Jun ZhangState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China.ORCID 0000-0002-6601-9180
Shengxiang GeState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China. sxge@xmu.edu.cn.ORCID 0000-0002-7165-3004
Shiyin ZhangState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China. zhangshiyin@xmu.edu.cn.ORCID 0000-0001-8291-7290
Ningshao XiaState Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, 361102, Fujian, China. nsxia@xmu.edu.cn.ORCID 0000-0003-0179-5266

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human enteroviruses (HEV) can cause a range of diseases from mild to potentially life-threatening. Identification and genotyping of HEV are crucial for disease management. Existing typing methods, however, have inherent limitations. Developing alternative methods to detect HEV with more virus types, high accuracy, and sensitivity in an accessible manner presents a technological and analytical challenge. Here, a sequence-specific nanoparticle barcode (SSNB) method is presented for simultaneous detection of 10 HEV types. This method significantly increases sensitivity, enhancing detection by 10-10

Indexed as

EnterovirusEnterovirus InfectionsNanoparticlesDNA Barcoding, TaxonomicGenotypeGenotyping TechniquesHumansRNA, ViralSensitivity and SpecificityRNA, Viral

Identifiers

PMID39090126
PMCPMC11294541

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.