Evidence map›Paper›PMID 39089879›Full record

ArticleLife science alliance2024

Activation mechanism and novel binding sites of the BK

Narasaem Lee, Subin Kim, Na Young Lee, Heeji Jo, Pyeonghwa Jeong, Haushabhau S Pagire, Suvarna H Pagire, Jin Hee Ahn, Mi Sun Jin, Chul-Seung Park

Abstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Narasaem LeeSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Subin KimSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Na Young LeeSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Heeji JoSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Pyeonghwa JeongDepartment of Chemistry, Duke University, Durham, NC, USA.
Haushabhau S PagireDepartment of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Suvarna H PagireDepartment of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Jin Hee AhnDepartment of Chemistry, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea.
Mi Sun JinSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea misunjin@gist.ac.kr.ORCID 0000-0003-0516-0284
Chul-Seung ParkSchool of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Republic of Korea cspark@gist.ac.kr.ORCID 0000-0003-0209-1412

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The large-conductance calcium-activated potassium (BK

Indexed as

Chloride Channel AgonistsCryoelectron MicroscopyLarge-Conductance Calcium-Activated Potassium ChannelsAnimalsBinding SitesCalciumHEK293 CellsHumansIon Channel GatingKineticsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLipid BilayersMutationProtein BindingCalciumChloride Channel AgonistsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium ChannelsLipid Bilayers

Identifiers

PMID39089879
PMCPMC11294680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.