Evidence map›Paper›PMID 39089357›Full record

ArticleAmerican journal of ophthalmology2024

Association Between Greater Social Vulnerability and Delayed Glaucoma Surgery.

Abdulla Shaheen, Felipe A Medeiros, Swarup S Swaminathan

Abstract read
In one paragraph

Article in American journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abdulla ShaheenFrom the Department of Ophthalmology, Bascom Palmer Eye Institute (A.S., F.A.M., S.S.S.), University of Miami Miller School of Medicine, Miami, Florida, USA.
Felipe A MedeirosFrom the Department of Ophthalmology, Bascom Palmer Eye Institute (A.S., F.A.M., S.S.S.), University of Miami Miller School of Medicine, Miami, Florida, USA.
Swarup S SwaminathanFrom the Department of Ophthalmology, Bascom Palmer Eye Institute (A.S., F.A.M., S.S.S.), University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address: sswaminathan@med.miami.edu.

Funding

Improving Individualized Assessments of Glaucoma Progression with Population-Based Electronic Health Record DataK23EY033831 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Swarup Sai Swaminathan · 2022 to 2026
$1.1M
NEI NIH HHS K23 EY033831
6 · The paper itself

Abstract

purposeTiming of surgical intervention in glaucoma is crucial to preserving sight. While ocular characteristics that increase surgical risk are known, the impact of neighborhood-level social risk factors such as the Social Vulnerability Index (SVI) and Area Deprivation Index (ADI) on time to glaucoma surgery is unknown. The objective of this study was to evaluate the association between SVI or ADI scores and the timing of glaucoma surgical intervention.

designRetrospective cohort study.

methodsAdult subjects with open-angle glaucoma were identified from the Bascom Palmer Glaucoma Repository using International Classification of Disease-10 codes. Subject demographics, ocular characteristics, and standard automated perimetry data were extracted. Geocoded data were obtained using subject residences and American Community Survey data. Univariable and multivariable time-to-event survival analyses using accelerated failure time models were completed to evaluate whether geocoded SVI and ADI scores accelerated or delayed time to glaucoma surgery from initial glaucoma diagnosis in the electronic health record.

resultsA total of 10,553 eyes from 6934 subjects were evaluated, of which 637 eyes (6.0%) from 568 subjects (8.2%) underwent glaucoma surgery. Mean age was 68.3 ± 13.5 years, with 57.9% female, 21.5% Black, and 34.5% Hispanic subjects. Mean follow-up time was 5.0 ± 2.1 years, with time to surgery of 3.2 ± 1.9 years. Multivariable accelerated failure time models demonstrated that higher mean intraocular pressure (time ratio [TR] 0.27 per 5 mm Hg higher; 95% confidence interval [CI]: 0.23-0.31, P < .001), faster standard automated perimetry rate of progression (TR 0.74 per 0.5 dB/year faster; 95% CI: 0.69-0.78, P < .001), moderate (TR 0.69; 95% CI: 0.56-0.85, P < .001) or severe baseline severity (TR 0.39; 95% CI: 0.32-0.47, P < .001), and thinner central corneal thickness (TR 0.85 per 50 µm thinner; 95% CI: 0.77-0.95, P = .003) all accelerated time to surgery. In contrast, overall SVI delayed surgery (TR 1.11 per 25% increase; 95% CI: 1.03-1.20, P = .006). Specifically, SVI Themes 1 (TR 1.08; 95% CI: 1.01-1.17, P = .037) and 4 (TR 1.11; 95% CI: 1.03-1.19, P = .006) were significant. Patients from the most deprived neighborhoods (highest national ADI quartile) had a 68% increase in time to surgery compared to the least deprived quartile (TR 1.68; 95% CI: 1.20-2.36, P = .002).

conclusionsResidence in areas with higher SVI or ADI scores was associated with delayed glaucoma surgery after controlling for demographic and ocular parameters. Awareness of such disparities can guide initiatives aimed at achieving parity in health outcomes.

Indexed as

Glaucoma, Open-AngleIntraocular PressureAgedAged, 80 and overFemaleFiltering SurgeryFollow-Up StudiesHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTime-to-TreatmentTrabeculectomyVisual FieldsVisual Field Tests

Identifiers

PMID39089357
PMCPMC11606798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.