Evidence map›Paper›PMID 39089194›Full record

ReviewAddictive behaviors2024

Urgent need for treatment addressing co-use of tobacco and cannabis: An updated review and considerations for future interventions.

Nhung Nguyen, Krysten W Bold, Erin A McClure

Abstract readReview
In one paragraph

Review in Addictive behaviors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  5. Change in Cigarette, Other Tobacco Product, and Cannabis Use Among Individuals Who Used or Did Not Use Cannabis During a Smoking Cessation Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nhung NguyenCenter for Tobacco Control Research and Education, University of California San Francisco, CA, USA; Division of General Internal Medicine, Department of Medicine, University of California San Francisco, CA, USA. Electronic address: nhung.nguyen@ucsf.edu.
Krysten W BoldDepartment of Psychiatry, Yale School of Medicine, CT, USA; Yale Cancer Center, CT, USA.
Erin A McClureDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, SC, USA; Hollings Cancer Center, Medical University of South Carolina, SC, USA.

Funding

SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
Determining the impact of cannabis use and severity on tobacco cessation outcomes: A prospective tobacco treatment trialR37CA237245 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MCCLURE, ERIN A · 2019 to 2025
$4.2M
The impact of cannabis and tobacco/nicotine product co-use in young adults: Prospective cessation evaluation and substitutionR01CA276066 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Erin A McClure · 2023 to 2026
$2.5M
Developing a smartphone-based intervention targeting high-risk situations of nicotine vaping among young adultsK01DA056693 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nhung Nguyen · 2024 to 2026
$575k
NCI NIH HHS R01 CA276066NCI NIH HHS R37 CA237245NIDA NIH HHS K01 DA056693NIDA NIH HHS K12 DA000167
6 · The paper itself

Abstract

backgroundThere are no clinical practice guidelines addressing the treatment of tobacco-cannabis co-use and a dearth of studies to inform treatment for co-use. This narrative review aims to (1) summarize promising intervention components used in published co-use treatment studies, (2) describe key gaps and emerging issues in co-use, and (3) provide recommendations and considerations in the development and evaluation of co-use interventions.

methodsWe conducted a literature search in June 2024 across several databases to update previous reviews on tobacco-cannabis co-use treatment. We found 9 published intervention studies that specifically addressed treatment for both substances. Data from these studies were manually extracted and summarized.

resultsMost of the 9 included studies (1) focused on acceptability and/or feasibility, (2) provided both psychosocial/behavioral and pharmacotherapy intervention components, (3) were conducted in adults, and (4) were delivered in-person, with some having digital asynchronous components, for a 5-to-12-week duration. The most common psychosocial/behavioral strategies used were Cognitive Behavioral Therapy, Motivational Interviewing, and Contingency Management; while the most common pharmacotherapy was Nicotine Replacement Therapy. There was no evidence of compensatory use of tobacco or cannabis when providing simultaneous treatment for both substances.

conclusionsThe literature to date provides support for well-integrated multi-component interventions of psychosocial/behavioral and pharmacotherapy strategies for co-use treatment. This review reinforces an urgent need for treatments targeting tobacco and cannabis co-use. Future interventions should address key gaps, including co-use of vaporized products among youth and young adults, tailored interventions for priority populations, and digital applications to increase reach and advance health equity.

Indexed as

Motivational InterviewingCognitive Behavioral TherapyHumansMarijuana AbuseTobacco Use Cessation DevicesCannabis use disorderMarijuanaPolysubstance useReviewSmoking cessationTobacco use disorderTreatment

Identifiers

PMID39089194
PMCPMC11365784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.