Evidence map›Paper›PMID 39089098›Full record

ArticleClinics (Sao Paulo, Brazil)2024

Correlation of serum Klotho, fetuin-A, and MGP levels with coronary artery calcification in maintenance hemodialysis patients.

Dan Wang, XiuLin Chu, JuHua Cao, YunHua Peng

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dan WangDepartment of East Hospital Nephrology, Yantaishan Hospital, Yantai City, Shandong Province, China.
XiuLin ChuDepartment of Nephrology, The People's Hospital of Xushui, Baoding City, Hebei Province, China.
JuHua CaoDepartment of Outpatient, The General Hospital of Western Theater Command of Chinese people's liberation army, Chengdu City, Sichuan Province, China.
YunHua PengDepartment of Nephrology, Dafeng People's Hospital, Yancheng City, JiangSu Province, China. Electronic address: wanglei_1346_gphc@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was to investigate the role of serum Klotho, fetuin-A, and Matrix Gla Protein (MGP) in Coronary Artery Calcification (CAC) in patients with Maintenance Hemodialysis (MHD) and their predictive value for CAC.

methods100 patients receiving MHD were selected. Serum Klotho, fetuin-A, and MGP levels were detected by ELISA. CAC scores were assessed by coronary CT scan. Multifactor analysis was used to evaluate the risk factors affecting CAC. The ability of serum Klotho, fetuin-A, and MGP levels to diagnose CAC was evaluated by receiver operating characteristic curves.

resultsSerum Klotho, fetuin-A, and MGP were independent risk factors for CAC. Serum Klotho, fetuin-A, and MGP were valuable in the diagnosis of CAC in MHD patients.

conclusionThere is a close relationship between Klotho, fetuin-A, and MGP levels in MHD patients and CAC.

Indexed as

alpha-2-HS-GlycoproteinBiomarkersCalcium-Binding ProteinsCoronary Artery DiseaseExtracellular Matrix ProteinsGlucuronidaseKlotho ProteinsMatrix Gla ProteinRenal DialysisVascular CalcificationAdultAgedCalcinosisEnzyme-Linked Immunosorbent AssayFemaleHumansalpha-2-HS-GlycoproteinBiomarkersCalcium-Binding ProteinsExtracellular Matrix ProteinsGlucuronidaseKlotho ProteinsKL protein, humanMatrix Gla ProteinCoronary artery calcificationFetuin-AKlothoMaintenance hemodialysis patientsMGP

Identifiers

PMID39089098
PMCPMC11342211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.