Evidence map›Paper›PMID 39088731›Full record

ArticleAIDS care2024

Who wants long-Acting injectable antiretroviral therapy? Treatment preferences among adults with HIV in Florida.

Rebecca J Fisk-Hoffman, Yiyang Liu, Charurut Somboonwit, Maya Widmeyer, Shantrel Canidate, Mattia Prosperi, Robert L Cook

Abstract read
In one paragraph

Article in AIDS care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rebecca J Fisk-HoffmanDepartment of Epidemiology, College of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL, USA.
Yiyang LiuDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, US.
Charurut SomboonwitDivision of Infectious Disease & International Medicine, Department of Internal Medicine, University of South Florida, Tampa, FL, USA.
Maya WidmeyerComprehensive Health Care, Unconditional Love Inc., Cocoa, FL, USA.
Shantrel CanidateDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, US.
Mattia ProsperiDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, US.
Robert L CookDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL, US.

Funding

Southern HIV and Alcohol Research Consortium Administrative and Research Support CoreU24AA022002 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L · 2012 to 2022
$5.5M
Technology-based assessments and intervention to reduce alcohol consumption and improve HIV viral suppression in the Florida CohortR01AA030481 · NIAAA · UNIVERSITY OF FLORIDA · PI Robert L Cook, Yan Wang · 2022 to 2026
$3.1M
Southern HIV and Alcohol Research Consortium Biomedical Data RepositoryU24AA029959 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L, WU, SAMUEL S · 2021 to 2025
$2.5M
Interest, Preference, and Uptake of Long Acting ART among PLWH in FloridaF31AA030518 · NIAAA · UNIVERSITY OF FLORIDA · PI HOFFMAN, REBECCA JEANNE FISK · 2022 to 2023
$83k
NIAAA NIH HHS F31 AA030518NIAAA NIH HHS R01 AA030481NIAAA NIH HHS U24 AA022002NIAAA NIH HHS U24 AA029959
6 · The paper itself

Abstract

Long-acting injectable (LAI) antiretroviral therapy (ART) is available to people with HIV (PWH), but it is unknown which PWH prefer this option. Using the Andersen Behavioral Model this study identifies characteristics of PWH with greater preference for LAI ART. Cross-sectional data from the Florida Cohort, which enrolled adult PWH from community-based clinics included information on predisposing (demographics), enabling (transportation, income), and need (ART adherence <90%) factors. ART preference was assessed via a single question (prefer pills, quarterly LAI, or no preference). Confounder-adjusted multinomial logistic regressions compared those who preferred pills to the other preference options, with covariates identified using directed acyclic graphs. Overall, 314 participants responded (40% non-Hispanic Black, 62% assigned male, 63% aged 50+). Most (63%) preferred the hypothetical LAI, 23% preferred pills, and 14% had no preference. PWH with access to a car (aRRR 1.97 95%CI 1.05-3.71), higher income (aRRR 2.55 95%CI 1.04-6.25), and suboptimal ART adherence (aRRR 7.41 95% CI 1.52-36.23) were more likely to prefer the LAI, while those who reported having no social network were less likely to prefer the LAI (aRRR 0.32 95% CI 0.11-0.88). Overall LAI interest was high, with greater preference associated with enabling and need factors.

Indexed as

Anti-HIV AgentsDrug MonitoringHIV InfectionsPatient PreferenceAdultCross-Sectional StudiesDelayed-Action PreparationsFemaleFloridaHumansInjectionsMaleMiddle AgedAnti-HIV AgentsDelayed-Action Preparationsantiretroviral therapyend-user preferencesHIVlong-acting antiretroviral therapySDG 3: Good health and well-being

Identifiers

PMID39088731
PMCPMC11511631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.