ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024
Leg cycling efficiency is unaltered in healthy aging regardless of sex or training status.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Chronic, self-reported fatigue in adult immunotherapy patients and healthy controls: No association with cardiopulmonary exercise testing parameters.Physiological reports · 2026Article
- Peak Power Output Is Equivalent to Peak Pulmonary Oxygen Consumption.Acta physiologica (Oxford, England) · 2026Article
- Resilience of the mitochondrial reticulum in aging.American journal of physiology. Endocrinology and metabolism · 2025Article
- Aging delays the suppression of lipolysis and fatty acid oxidation in the postprandial period.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
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Authors and funding
5 authors.
Funding
Abstract
Muscular efficiency during exercise has been used to interrogate aspects of human muscle energetics, including mitochondrial coupling and biomechanical efficiencies. Typically, assessments of muscular efficiency have involved graded exercises. Results of previous studies have been interpreted to indicate a decline in exercise efficiency with aging owing to decreased mitochondrial function. However, discrepancies in variables such as exercise stage duration, cycling cadence, and treadmill walking mechanics may have affected interpretations of results. Furthermore, recent data from our lab examining the ATP to oxygen ratio (P:O) in mitochondrial preparations isolated from NIA mouse skeletal muscle showed no change with aging. Thus, we hypothesized that delta efficiency (Δ€) during steady-rate cycling exercise would not be altered in older healthy subjects compared with young counterparts regardless of biological sex or training status. Young (21-35 yr) and older (60-80 yr) men (
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Registered trials
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