Evidence map›Paper›PMID 39088444›Full record

ArticlePLOS global public health2024

COVID-19 vaccine effectiveness among South Asians in Canada.

Rahul Chanchlani, Baiju R Shah, Shrikant I Bangdiwala, Russell J de Souza, Jin Luo, Shelly Bolotin, Dawn M E Bowdish, Dipika Desai, Karl Everett, Scott A Lear and 5 more

Erratum issuedAbstract read
In one paragraph

Article in PLOS global public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Rahul ChanchlaniDivision of Pediatric Nephrology, Department of Pediatrics, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Baiju R ShahICES, Toronto, Ontario, Canada.
Shrikant I BangdiwalaPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Russell J de SouzaPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Jin LuoICES, Toronto, Ontario, Canada.
Shelly BolotinCentre for Vaccine Preventable Diseases, University of Toronto, Toronto, Ontario, Canada.
Dawn M E BowdishFirestone Institute for Respiratory Health, St. Joseph's Healthcare, St. Joseph's Healthcare, Hamilton, Ontario, Canada.
Dipika DesaiChanchlani Research Centre, McMaster University, Hamilton, Ontario, Canada.
Karl EverettICES, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-5437-6658
Scott A LearSimon Fraser University, Burnaby, British Columbia, Canada.ORCID https://orcid.org/0000-0001-7614-755X
Mark LoebPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Zubin PunthakeePopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Diana SherifaliPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Gita WahiChanchlani Research Centre, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0001-5943-9702
Sonia S AnandChanchlani Research Centre, McMaster University, Hamilton, Ontario, Canada.ORCID https://orcid.org/0000-0003-3692-7441

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the effectiveness of COVID-19 vaccines among South Asians living in Ontario, Canada compared to non-South Asians and compared the odds of symptomatic COVID-19 infection and related hospitalizations and deaths among non-vaccinated South Asians and non-South Asians. This was a test negative design study conducted in Ontario, Canada between December 14, 2020 and November 15, 2021. All eligible individuals >18 years with symptoms of COVID-19 were subdivided by ethnicity (South Asian vs other) and vaccination status (vaccinated versus not). The primary outcome was vaccine effectiveness as defined by COVID-19 infections, hospitalizations, and deaths, and secondary outcome was the odds of COVID-19 infections, hospitalizations, and death comparing non-vaccinated South Asians to non-vaccinated non-South Asians. 883,155 individuals were included. Among South Asians, two doses of COVID-19 vaccine prevented 93.8% (95% CI 93.2, 94.4) of COVID-19 infections and 97.5% (95% CI 95.2, 98.6) of hospitalizations and deaths. Among non-South Asians, vaccines prevented 86.6% (CI 86.3, 86.9) of COVID-19 infections and 93.1% (CI 92.2, 93.8) of hospitalizations and deaths. Non-vaccinated South Asians had higher odds of symptomatic SARS-CoV-2 infection compared to non-vaccinated non-South Asians (OR 2.35, 95% CI 2.3, 2.4), regardless of their immigration status. COVID-19 vaccines are effective in preventing infections, hospitalizations and deaths among South Asians living in Canada. The observation that non-vaccinated South Asians have higher odds of symptomatic COVID-19 infection warrants further investigation.

Identifiers

PMID39088444
PMCPMC11293718

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.