Evidence map›Paper›PMID 39088396›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.

Meijiao Gong, Françoise Myster, Abdulkader Azouz, Guillem Sanchez Sanchez, Shifang Li, Benoit Charloteaux, Bin Yang, Jenna Nichols, Lucas Lefevre, Justine Javaux and 13 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Meijiao Gong *Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.ORCID 0000-0001-8328-9804
Françoise Myster *Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.ORCID 0009-0000-7147-480X
Abdulkader AzouzInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies 6041, Belgium.
Guillem Sanchez SanchezInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies 6041, Belgium.
Shifang LiDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.
Benoit CharloteauxGroupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA), GIGA-Genomics core facility, University of Liège, Liège 4000, Belgium.ORCID 0000-0003-4282-9688
Bin YangDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.ORCID 0009-0002-5697-3226
Jenna NicholsMedical Research Council (MRC)-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, United Kingdom.ORCID 0000-0003-0093-7170
Lucas LefevreThe Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdom.
Justine JavauxDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.
Sylvain LeemansDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.
Olivier NivellesDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.
Willem van CampeSciensano, Scientific Directorate Infectious Diseases in Animals, Experimental Center Machelen, Machelen 1830, Belgium.
Stefan RoelsSciensano, Scientific Directorate Infectious Diseases in Animals, Experimental Center Machelen, Machelen 1830, Belgium.ORCID 0009-0006-4119-8027
Laurent MostinSciensano, Scientific Directorate Infectious Diseases in Animals, Experimental Center Machelen, Machelen 1830, Belgium.ORCID 0009-0006-0789-2656
Thierry van den BergSciensano, Scientific Directorate Infectious Diseases in Animals, Experimental Center Machelen, Machelen 1830, Belgium.
Andrew J DavisonMedical Research Council (MRC)-University of Glasgow Centre for Virus Research, Glasgow G61 1QH, United Kingdom.ORCID 0000-0002-4991-9128
Laurent GilletDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.ORCID 0000-0002-1047-2525
Timothy ConnelleyThe Roslin Institute, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, United Kingdom.
David VermijlenInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies 6041, Belgium.ORCID 0000-0002-7605-8845
Stanislas GorielyInstitute for Medical Immunology, Université Libre de Bruxelles, Gosselies 6041, Belgium.
Alain VanderplasschenDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.
Benjamin G DewalsDepartment of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine-Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, Liège 4000, Belgium.ORCID 0000-0003-1497-0799

Funding

EC | European Regional Development Fund (ERDF) 411132-957270Fonds De La Recherche Scientifique - FNRS (FNRS) J.0225.20; F.4501.15; T.0067.21; 7.4586.19; 7.6529.21; J.0094.15; T.0241.19Walloon excellence in life sciences and biotechnology (WELBIO) A-14 12; A-15
6 · The paper itself

Abstract

Alcelaphine gammaherpesvirus 1 (AlHV-1) asymptomatically persists in its natural host, the wildebeest. However, cross-species transmission to cattle results in the induction of an acute and lethal peripheral T cell lymphoma-like disease (PTCL), named malignant catarrhal fever (MCF). Our previous findings demonstrated an essential role for viral genome maintenance in infected CD8

Indexed as

CD8-Positive T-LymphocytesGammaherpesvirinaeAnimalsCattleHerpesviridae InfectionsMalignant CatarrhCD8+ T cellsepigenomicsmalignant catarrhal feverperipheral T cell lymphomatranscriptomics

Identifiers

PMID39088396
PMCPMC11317613

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.