Evidence map›Paper›PMID 39088248›Full record

ArticleMicrobiology (Reading, England)2024

A new model of endotracheal tube biofilm identifies combinations of matrix-degrading enzymes and antimicrobials able to eradicate biofilms of pathogens that cause ventilator-associated pneumonia.

Dean Walsh, Chris Parmenter, Saskia E Bakker, Trevor Lithgow, Ana Traven, Freya Harrison

Abstract read
In one paragraph

Article in Microbiology (Reading, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Mucofilm: a nexus for phage-microbiome interactions in gut ecology.Applied and environmental microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dean WalshSchool of Life Sciences, University of Warwick, Coventry, UK.
Chris ParmenterNanoscale and Microscale Research Centre, University of Nottingham, Nottingham, UK.
Saskia E BakkerSchool of Life Sciences, University of Warwick, Coventry, UK.
Trevor LithgowDepartment of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton 3800, Victoria, Australia.
Ana TravenDepartment of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University, Clayton 3800, Victoria, Australia.
Freya HarrisonSchool of Life Sciences, University of Warwick, Coventry, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ventilator-associated pneumonia is defined as pneumonia that develops in a patient who has been on mechanical ventilation for more than 48 hours through an endotracheal tube. It is caused by biofilm formation on the indwelling tube, which introduces pathogenic microbes such as

Indexed as

BiofilmsCandida albicansKlebsiella pneumoniaePneumonia, Ventilator-AssociatedPseudomonas aeruginosaAnti-Bacterial AgentsAnti-Infective AgentsHumansIntubation, IntratrachealAnti-Bacterial AgentsAnti-Infective Agentsantimicrobial resistanceantimicrobial tolerancebiofilmendotracheal tubehospital-acquired infectioninfection

Identifiers

PMID39088248
PMCPMC11541551

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.