Evidence map›Paper›PMID 39088181›Full record

ArticleEuropean geriatric medicine2024

Agreement and predictive value of the clinical frailty scale in hospitalized older patients.

Liese Lanckmans, Olga Theou, Nele Van Den Noortgate, Ruth Piers

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Article in European geriatric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Liese LanckmansDepartment of Geriatrics, Ghent University Hospital, Ghent, Belgium.ORCID 0009-0006-6522-4939
Olga TheouSchool of Physiotherapy, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0001-6460-782X
Nele Van Den NoortgateDepartment of Geriatrics, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0001-5546-5380
Ruth PiersDepartment of Geriatrics, Ghent University Hospital, Ghent, Belgium. Ruth.Piers@uzgent.be.ORCID 0000-0001-5261-220X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur objective was to perform an external validity study of the clinical frailty scale (CFS) classification tree by determining the agreement of the CFS when attributed by a senior geriatrician, a junior geriatrician, or using the classification tree. Additionally, we evaluated the predictive value of the CFS for 6-month mortality after admission to an acute geriatric unit.

methodsThis prospective study was conducted in two acute geriatric units in Belgium. The premorbid CFS was determined by a senior and a junior geriatrician based on clinical judgment within the first 72 h of admission. Another junior geriatrician, who did not have a treatment relationship with the patient, scored the CFS using the classification tree. Intra-class correlation coefficient (ICC) was calculated to assess agreement. A ROC curve and Cox regression model determined prognostic value.

resultsIn total, 97 patients were included (mean age 86 ± 5.2; 66% female). Agreement of the CFS, when determined by the senior geriatrician and the classification tree, was moderate (ICC 0.526, 95% CI [0.366-0.656]). This is similar to the agreement between the senior and junior geriatricians' CFS (ICC 0.643, 95% CI [0.510-0.746]). The AUC for 6-month mortality based on the CFS by respectively the classification tree, the senior and junior geriatrician was 0.719, 95% CI [0.592-0.846]; 0.774, 95% CI [0.673-0.875]; 0.774, 95% CI [0.665-0.882]. Cox regression analysis indicated that severe or very severe frailty was associated with a higher risk of mortality compared to mild or moderate frailty (hazard ratio respectively 6.274, 95% CI [2.613-15.062] by the classification tree; 3.476, 95% CI [1.531-7.888] by the senior geriatrician; 4.851, 95% CI [1.891-12.442] by the junior geriatrician).

conclusionInterrater agreement in CFS scoring on clinical judgment without Comprehensive Geriatric Assessment is moderate. The CFS classification tree can help standardize CFS scoring.

Indexed as

Frail ElderlyFrailtyGeriatric AssessmentHospitalizationAgedAged, 80 and overBelgiumFemaleHumansMalePredictive Value of TestsPrognosisProportional Hazards ModelsProspective StudiesROC CurveAcute geriatric unitAgreementClassification treeClinical frailty scaleMortality

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.