Evidence map›Paper›PMID 39087873›Full record

ArticleThe journal of physical chemistry letters2024

The Effects of Electric Fields on Protein Phase Behavior and Protein Crystallization Kinetics.

D Ray, M Madani, J K G Dhont, F Platten, K Kang

Abstract read
In one paragraph

Article in The journal of physical chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. A multiscaleJournal of applied crystallography · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

D RayInstitute of Biological Information Processing IBI-4, Forschungszentrum Jülich, 52428, Jülich, Germany.
M MadaniFaculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0003-4149-8485
J K G DhontInstitute of Biological Information Processing IBI-4, Forschungszentrum Jülich, 52428, Jülich, Germany.
F PlattenInstitute of Biological Information Processing IBI-4, Forschungszentrum Jülich, 52428, Jülich, Germany.ORCID 0000-0001-5912-1833
K KangInstitute of Biological Information Processing IBI-4, Forschungszentrum Jülich, 52428, Jülich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We experimentally studied the effects of an externally applied electric field on protein crystallization and liquid-liquid phase separation (LLPS) and its crystallization kinetics. For a surprisingly weak alternating current (AC) electric field, crystallization was found to occur in a wider region of the phase diagram, while nucleation induction times were reduced, and crystal growth rates were enhanced. LLPS on the contrary was suppressed, which diminishes the tendency for a two-step crystallization scenario. The effect of the electric field is ascribed to a change in the protein-protein interaction potential.

Indexed as

CrystallizationElectricityKineticsMuramidasePhase TransitionProteinsMuramidaseProteins

Identifiers

PMID39087873
PMCPMC11318033

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.