Evidence map›Paper›PMID 39087788›Full record

ArticlemSphere2024

Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to high-level amoxicillin resistance of

Alain Cimuanga-Mukanya, Evariste Tshibangu-Kabamba, Patrick de Jesus Ngoma Kisoko, Kartika Afrida Fauzia, Fabien Mbaya Tshibangu, Antoine Tshimpi Wola, Pascal Tshiamala Kashala, Dieudonné Mumba Ngoyi, Steve Ahuka-Mundeke, Gunturu Revathi and 5 more

Abstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Challenges and Prospects for Eradication ofPathogens (Basel, Switzerland) · 2025
    Review
  2. Molecular Mechanisms of Biofilm Formation inAntibiotics (Basel, Switzerland) · 2024
    Review
  3. Frontiers in cellular and infection microbiology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alain Cimuanga-MukanyaDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Oita, Japan.ORCID 0000-0002-9255-3627
Evariste Tshibangu-KabambaDepartment of Internal Medicine, Faculty of Medicine, Pharmacy and Public Health, University of Mbujimayi, Mbujimayi, Democratic Republic of Congo.
Patrick de Jesus Ngoma KisokoDepartment of Internal Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Kartika Afrida FauziaResearch Centre for Preclinical and Clinical Medicine, National Research and Innovation Agency, Cibinong Science Center, West Java, Indonesia.
Fabien Mbaya TshibanguDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Oita, Japan.
Antoine Tshimpi WolaDepartment of Internal Medicine, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of Congo.
Pascal Tshiamala KashalaAstrid Clinics, Gastroenterology and Hepatology Section, Kinshasa, Democratic Republic of Congo.
Dieudonné Mumba NgoyiDepartment of Parasitology, National Institute of Biomedical Research (INRB), Kinshasa, Democratic Republic of Congo.
Steve Ahuka-MundekeDepartment of Virology, National Institute of Biomedical Research (INRB), Kinshasa, Democratic Republic of Congo.
Gunturu RevathiDepartment of Clinical Microbiology, Aga Khan University Hospital, Nairobi, Kenya.
Ghislain Disashi-TumbaDepartment of Internal Medicine, Faculty of Medicine, Pharmacy and Public Health, University of Mbujimayi, Mbujimayi, Democratic Republic of Congo.
Yasutoshi KidoDepartment of Virology and Parasitology & Research Center for Infectious Disease Sciences, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan.
Takashi MatsumotoDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Oita, Japan.
Junko AkadaDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Oita, Japan.
Yoshio YamaokaDepartment of Environmental and Preventive Medicine, Faculty of Medicine, Oita University, Oita, Japan.ORCID 0000-0002-1222-5819

Funding

REGULATION OF CXC CHEMOKINE EXPRESSION BY H. PYLORIR01DK062813 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI YAMAOKA, YOSHIO · 2004 to 2013
$3.0M
NIDDK NIH HHS R01 DK062813
6 · The paper itself

Abstract

The growing resistance to amoxicillin (AMX)-one of the main antibiotics used in

Indexed as

Amino Acid SubstitutionAmoxicillinAnti-Bacterial AgentsDrug Resistance, BacterialHelicobacter pyloriMicrobial Sensitivity TestsPenicillin-Binding ProteinsBacterial ProteinsHelicobacter InfectionsHumansMutationAmoxicillinAnti-Bacterial AgentsBacterial ProteinsPenicillin-Binding Proteinsamoxicillin resistanceHelicobacter pylorimutationspenicillin-binding protein 1A

Identifiers

PMID39087788
PMCPMC11351044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.