Evidence map›Paper›PMID 39087765›Full record

ArticleJournal of virology2024

The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence.

James Alwine, Felicia Goodrum, Bruce Banfield, David Bloom, William J Britt, Andrew J Broadbent, Samuel K Campos, Arturo Casadevall, Gary C Chan, Anna R Cliffe and 31 more

Abstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

James AlwineDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.ORCID 0009-0009-5854-1540
Felicia GoodrumDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0002-6646-7290
Bruce BanfieldDepartment of Biomedical and Molecular Sciences, Queens University, Kingston, Ontario, Canada.ORCID 0000-0002-5989-6695
David BloomDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida, USA.ORCID 0000-0001-5935-8494
William J BrittDepartment of Pediatrics, University of Alabama, Birmingham, Birmingham, Alabama, USA.
Andrew J BroadbentDepartment of Animal and Avian Sciences, University of Maryland, College Park, Maryland, USA.ORCID 0000-0002-4716-1835
Samuel K CamposDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0003-1540-9821
Arturo CasadevallJohns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-9402-9167
Gary C ChanDepartment of Microbiology and Immunology, SUNY Upstate Medical University, Syracuse, New York, USA.ORCID 0000-0001-8209-9777
Anna R CliffeDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Terence DermodyDepartment of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1853-8741
Paul DuprexUniversity of Pittsburgh, Center for Vaccine Research, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-1716-6376
Lynn W EnquistDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0001-9968-8586
Klaus FruehOregon Health and Science University, Vaccine and Gene Therapy Institute, Beaverton, Oregon, USA.
Adam P GeballeDepartment of Medicine, University of Washington, Fred Hutchinson Cancer Center, Seattle, Washington, USA.ORCID 0000-0002-9279-6653
Marta GagliaDepartment of Medical Microbiology and Immunology, University of Wisconsin, Institute for Molecular Virology, Madison, Wisconsin, USA.ORCID 0000-0002-1791-0663
Stephen GoldsteinDepartment of Human Genetics, University of Utah School of Medicine, Howard Hughes Medical Institute, Salt Lake City, Utah, USA.
Alexander L GreningerDepartment of Medicine, Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Gigi Kwick GronvallJohns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-2514-146X
Jae U JungCleveland Clinic, Lerner Research Institute, Cleveland, Ohio, USA.ORCID 0000-0003-4559-8774
Jeremy P KamilDepartment of Microbiology and Immunology, Louisiana State University Health Sciences, Shreveport, Louisiana, USA.ORCID 0000-0001-8422-7656
Seema LakdawalaDepartment of Microbiology and Immunology, Emory University, Atlanta, Georgia, USA.ORCID 0000-0002-7679-2150
Shan-Lu LiuThe Ohio State University, Center for Retrovirus Research and Infectious Disease Institute, Columbus, Ohio, USA.ORCID 0000-0003-1620-3817
Micah LuftigDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-2964-1907
John P MooreDepartment of Microbiology and Immunology, Cornell University, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-9902-6096
Anne MosconaColumbia University, Vagelos College of Physicians and Surgeons, New York, New York, USA.ORCID 0000-0002-1796-8320
Benjamin W NeumanDepartment of Biology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-1240-8954
Janko Ž NikolichDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0001-5830-5323
Christine O'ConnorCleveland Clinic, Lerner Research Institute, Cleveland, Ohio, USA.ORCID 0000-0003-4943-3774
Andrew PekoszJohns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0003-3248-1761
Sallie PermarDepartment of Pediatrics, Cornell University, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-1438-4554
Julie PfeifferUniversity of Texas, Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0003-2973-4895
John PurdyDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.ORCID 0000-0001-7460-7567
Angela RasmussenUniversity of Saskatchewan, College of Medicine, Saskatoon, Canada.ORCID 0000-0001-9462-3169
Bert SemlerDepartment of Microbiology and Molecular Genetics, University of California, Irvine, Irvine, California, USA.ORCID 0000-0002-2424-5155
Gregory A SmithDepartment of Microbiology and Immunology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0001-9644-8472
David A SteinOregon State University, Carlson College of Veterinary Medicine, Corvallis, Oregon, USA.
Koenraad Van DoorslaerDepartment of Immunobiology, University of Arizona, Tucson, Arizona, USA.
Sandra K WellerDepartment of Molecular Biology and Biophysics, University of Connecticut, Farmington, Connecticut, USA.ORCID 0000-0002-4519-6276
Sean P J WhelanWashington University School of Medicine in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0003-1564-8590
Andrew YurochkoDepartment of Microbiology and Immunology, Louisiana State University Health Sciences, Shreveport, Louisiana, USA.ORCID 0000-0002-6452-5813

Funding

Project 4-Tracking cytomegalovirus-primed long-lived NK cells in salivary glandP20GM134974 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ANDREW D YUROCHKO · 2021 to 2026
$15.0M
6 · The paper itself

Abstract

Science is humanity's best insurance against threats from nature, but it is a fragile enterprise that must be nourished and protected. The preponderance of scientific evidence indicates a natural origin for SARS-CoV-2. Yet, the theory that SARS-CoV-2 was engineered in and escaped from a lab dominates media attention, even in the absence of strong evidence. We discuss how the resulting anti-science movement puts the research community, scientific research, and pandemic preparedness at risk.

Indexed as

COVID-19SARS-CoV-2AnimalsHumansPandemicsanti-scienceCOVID-19lab leakoriginpandemicSARS-CoV-2science advocacyscience policyspilloverzoonosis

Identifiers

PMID39087765
PMCPMC11406950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.