Evidence map›Paper›PMID 39087107›Full record

ArticleWorld journal of gastrointestinal surgery2024

Spleen volume is associated with overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with portal hypertension.

Chun-Juan Zhao, Chao Ren, Zhen Yuan, Guo-Hui Bai, Jin-Yu Li, Long Gao, Jin-Hui Li, Ze-Qi Duan, Dui-Ping Feng, Hui Zhang

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Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Chun-Juan ZhaoCollege of Medical Imaging, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Chao RenCollege of Medical Imaging, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Zhen YuanDepartment of Occupational Health, School of Public Health, Shanxi Key Laboratory of Environmental Health Impairment and Prevention, NHC Key Laboratory of Pneumoconiosis, MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Guo-Hui BaiCollege of Medical Imaging, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Jin-Yu LiDepartment of Oncological and Vascular Intervention, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Long GaoDepartment of Oncological and Vascular Intervention, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Jin-Hui LiCollege of Medical Imaging, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Ze-Qi DuanFirst Clinical Medical College, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Dui-Ping FengDepartment of Oncological and Vascular Intervention, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Hui ZhangCollege of Medical Imaging, Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortal shunt and immune status related to the spleen are related to the occurrence of hepatic encephalopathy (HE). It is unknown whether spleen volume before transjugular intrahepatic portosystemic shunt (TIPS) is related to postoperative HE.

aimTo investigate the relationship between spleen volume and the occurrence of HE.

methodsThis study included 135 patients with liver cirrhosis who underwent TIPS, and liver and spleen volumes were elevated upon computed tomography imaging. The Kaplan-Meier curve was used to compare the difference in the incidence rate of HE among patients with different spleen volumes. Univariate and multivariate Cox regression analyses were performed to identify the factors affecting overt HE (OHE). Restricted cubic spline was used to examine the shapes of the dose-response association between spleen volumes and OHE risk.

resultsThe results showed that 37 (27.2%) of 135 patients experienced OHE during a 1-year follow-up period. Compared with preoperative spleen volume (901.30 ± 471.90 cm

conclusionSpleen volume is related to the occurrence of OHE after TIPS. Preoperative spleen volume is an independent risk factor for post-TIPS OHE.

Indexed as

CirrhosisHepatic encephalopathyPortal hypertensionSpleen volumeTransjugular intrahepatic portosystemic shunt

Identifiers

PMID39087107
PMCPMC11287704

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