Evidence map›Paper›PMID 39087061›Full record

ArticleJournal of radiosurgery and SBRT2024

Patient and physician attitudes towards salvage stereotactic radiosurgery or radiotherapy for brain metastases.

Benjamin J Rich, Timoteo Almeida, Jared A Maas, Shahil Mehta, Raj Singh, Haley K Perlow, Benjamin Silver, Eric J Lehrer, Yash Soni, William H Jin and 8 more

Abstract read
In one paragraph

Article in Journal of radiosurgery and SBRT, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Benjamin J RichDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Timoteo AlmeidaDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Jared A MaasDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Shahil MehtaDepartment of Radiation Oncology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Raj SinghDepartment of Radiation Oncology, Virginia Commonwealth University Health System, Richmond, VA, USA.
Haley K PerlowDepartment of Radiation Oncology, Ohio State University Wexner Medical Center, Columbus, OH, USA.
Benjamin SilverDepartment of Radiation Oncology, State University of New York Downstate Medical Center, Brooklyn, NY, USA.
Eric J LehrerDepartment of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY USA.
Yash SoniDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
William H JinDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Crystal S SeldonDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Gregory AzzamDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Raphael YechieliDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Gregory KubicekDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Ricardo J KomotarDepartment of Neurosurgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Carolina G BenjaminDepartment of Neurosurgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Tejan DiwanjiDepartment of Radiation Oncology, South Baltimore County Medical Center, Halethorpe, MD, USA.
Eric A MellonDepartment of Radiation Oncology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The experience of patients with brain metastases treated with stereotactic radiosurgery (SRS) may shape attitudes towards salvage therapy. Furthermore, physician attitudes towards salvage therapy may differ based on specialty and experience. Our objective is to compare physician attitudes and patient experiences with SRS. Methods: Eligible patients with brain metastases treated with one course of SRS or fractionated stereotactic radiotherapy (FSRT) without whole brain radiotherapy (WBRT) in the definitive or postoperative setting at a single institution were surveyed from 11/2021 to 11/2022 regarding their perspectives on salvage therapy. A separate 11-question multi-disciplinary physician survey was distributed to residents, fellows and attendings at seven additional academic institutions in the US. Chi-square test and Mann-Whitney U test were used to assess differences. Results: A total of 30 patients and 88 physicians were surveyed. Most patients reported being satisfied or very satisfied with initial SRS/FSRT (90%). When given an option between WBRT or SRS for salvage treatment, all patients favored SRS. The physicians consisted of radiation oncologists (69.3%), neurosurgeons (19.3%), medical oncologists (8.0%), and neuro-oncologists (3.4%). Most physicians were confident or very confident in their ability to discuss the risks and benefits of SRS for brain metastases (78.9%), but this was significantly lower if the patient had received prior SRS (56.6%, P<.001). In these cases, there were significant differences in response by medical specialty and confidence level (P<0.05). Conclusions: Patients and physicians view tumor control followed by long-term toxicity as the most important factors for salvage therapy after initial SRS for brain metastases.

Indexed as

brain metastasisquality of liferadiosurgeryradiotherapysurvey

Identifiers

PMID39087061
PMCPMC11288657

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.