Evidence map›Paper›PMID 39086788›Full record

ArticleCureus2024

Fatal Myocarditis in Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) Without Mortality-Related Risk Factors: A Case Report and Literature Review.

Aya Watanabe, Yohei Nakamoto, Tetsuro Aita, Toru Naganuma, Sei Takahashi, Yuichiro Kiko, Hiroaki Nakagawa, Sugihiro Hamaguchi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aya WatanabeDepartment of General Internal Medicine, Fukushima Medical University, Fukushima, JPN.
Yohei NakamotoDepartment of General Internal Medicine, Fukushima Medical University, Fukushima, JPN.
Tetsuro AitaDepartment of General Internal Medicine, Fukushima Medical University, Fukushima, JPN.
Toru NaganumaDepartment of General Internal Medicine, Futaba Emergency and General Medicine Support Center, Fukushima Medical University, Fukushima, JPN.
Sei TakahashiDepartment of General Internal Medicine, Futaba Emergency and General Medicine Support Center, Fukushima Medical University, Fukushima, JPN.
Yuichiro KikoDepartment of Diagnostic Pathology, Fukushima Medical University, Fukushima, JPN.
Hiroaki NakagawaDepartment of General Internal Medicine, Center for Innovative Research for Communities and Clinical Excellence, Fukushima Medical University, Fukushima, JPN.
Sugihiro HamaguchiDepartment of General Internal Medicine, Fukushima Medical University, Fukushima, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug reaction characterized by skin rash, organ involvement, lymph node swelling, eosinophilia, and atypical lymphocytosis, with myocarditis being a rare but potentially fatal complication. It has been reported that in patients with cardiac involvement due to DRESS, older age and shorter periods between offending drug exposure and symptom onset are associated with mortality. We report a case of fatal DRESS-associated myocarditis in a young woman, occurring one month after drug exposure, despite intensive immunosuppressive therapy. This case report highlights the risk of mortality from DRESS-associated myocarditis even in patients lacking known risk factors.

Indexed as

drug reaction with eosinophilia and systemic symptoms (dress)eosinophilic myocarditishhv6latent periodmortality-related risk factorsmyocardial biopsy

Identifiers

PMID39086788
PMCPMC11289355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.