Evidence map›Paper›PMID 39086675›Full record

ArticleFrontiers in molecular medicine2023

Phase I-II study using DeltaRex-G, a tumor-targeted retrovector encoding a cyclin G1 inhibitor for metastatic carcinoma of breast.

Howard W Bruckner, Sant P Chawla, Nadezhda Omelchenko, Don A Brigham, Erlinda M Gordon

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04091295 (BLESSED), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04091295 availablenot on this map

BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast

Typeexpanded_accessSponsorAveni FoundationConditionsPancreatic Cancer, Osteosarcoma, MPNST (Malignant Peripheral Nerve Sheath Tumor), ChondrosarcomaArmsDNG64-CAR-V
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Howard W BrucknerBruckner Oncology, New York, NY, United States.
Sant P ChawlaCancer Center of Southern California, Santa Monica, CA, United States.
Nadezhda OmelchenkoCancer Center of Southern California, Santa Monica, CA, United States.
Don A BrighamAveni Foundation, Santa Monica, CA, United States.
Erlinda M GordonCancer Center of Southern California, Santa Monica, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer gene therapyCCNG1cell cycle controlcyclin G1 inhibitorDeltaRex-GDeltaVaximmunotherapymetastatic breast cancer

Identifiers

PMID39086675
PMCPMC11285576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.