Evidence map›Paper›PMID 39086391›Full record

ReviewFrontiers in pharmacology2024

Application of network pharmacology in traditional Chinese medicine for the treatment of digestive system diseases.

Shihao Zheng, Yijun Liang, Tianyu Xue, Wei Wang, Size Li, Peng Zhang, Xiaoke Li, Xu Cao, Qiyao Liu, Wenying Qi and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shihao Zheng *Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yijun Liang *Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China.
Tianyu Xue *First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, China.
Wei Wang *Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Size LiDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Peng ZhangDongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xiaoke LiDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xu CaoDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Qiyao LiuDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Wenying QiDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yongan YeDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xiaobin ZaoDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the general improvement in living standards in recent years, people's living habits, including their dietary habits, have changed. More people around the world do not follow a healthy diet, leading to an increase in morbidity and even mortality due to digestive system diseases, which shows an increasing trend every year. The advantage of traditional Chinese medicine (TCM) in treating digestive system diseases is evident. Consequently, the mechanisms of action of single Chinese herbs and compound Chinese medicines have become the focus of research. The research method of the network pharmacology system was highly consistent with the holistic concept of TCM, and provided a new perspective and theoretical basis for basic research on digestive system diseases. This article summarizes the common databases currently used in research on TCM. It also briefly introduces the basic methods and technologies of network pharmacology studies. It also summarizes the advancements of network pharmacology technology through a comprehensive literature search on PubMed. Based on this analysis, we further explored the role of TCM in treating digestive system diseases, including chronic gastritis, gastric cancer, ulcerative colitis, and liver cirrhosis. This study provides new ideas and references for treating digestive system diseases with TCM in the future and serves as a reference for relevant researchers.

Indexed as

compoundsdigestive system diseasesnetwork pharmacologytargetstraditional Chinese medicine

Identifiers

PMID39086391
PMCPMC11289720

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.