Evidence map›Paper›PMID 39085936›Full record

ArticleJournal of health, population, and nutrition2024

A healthful plant-based diet can reduce the risk of developing colorectal cancer: case-control study.

Sazin Yarmand, Bahram Rashidkhani, Arezoo Alimohammadi, Zainab Shateri, Mahboobeh Shakeri, Zahra Sohrabi, Mehran Nouri

Abstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sazin YarmandDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Bahram RashidkhaniDepartment of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Arezoo AlimohammadiDepartment of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Zainab ShateriDepartment of Nutrition and Biochemistry, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.ORCID 0000-0003-3725-6686
Mahboobeh ShakeriEndoocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra SohrabiDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. zahra_2043@yahoo.com.ORCID 0000-0003-4572-3942
Mehran NouriCancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. mehran_nouri71@yahoo.com.ORCID 0000-0002-7031-3542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe benefit of adherence to a plant-based diet concerning colorectal cancer (CRC) has not been investigated among Middle Eastern population. This study aimed to investigate how adherence to a plant-based diet influences the risk of CRC in this understudied population.

methodsThis case-control study was conducted in the CRC surgery departments of general hospitals in Tehran, Iran. A total of 71 individuals with newly diagnosed CRC (cases) and 142 controls subjects free of cancer and acute illness were concurrently recruited from the same hospital. Dietary information was collected using a semi-quantitative 168-item food frequency questionnaire. Dietary patterns were characterized using the plant-based diet index (PDI), unhealthy plant-based diet index (uPDI) and healthy plant-based diet index (hPDI). Multivariate logistic regression was employed to assess the association between these dietary patterns and the risk of CRC.

resultsAfter adjusting the potential confounders, the risk of CRC was significantly lower in the highest tertile of hPDI compared to the lowest tertile (odds ratio (OR) = 0.21; 95% confidence interval (CI): 0.07-0.56, representing 79% risk reduction). Conversely, the risk of CRC was significantly higher in the highest tertile of uPDI compared to the lowest tertile (OR = 6.76; 95% CI: 2.41-18.94). PDI was no significant associated with the risk of CRC.

conclusionsThis study found that higher scores on the hPDI was significantly associated with a decrease risk of CRC, while greater adherence to the uPDI contributed to a significantly increase risk.

Indexed as

Colorectal NeoplasmsDiet, HealthyDiet, VegetarianAdultAgedCase-Control StudiesDiet, Plant-BasedFemaleHumansIranLogistic ModelsMaleMiddle AgedRisk FactorsColorectal cancerColorectal neoplasmsDietsPlant-basedPlant-based diet

Identifiers

PMID39085936
PMCPMC11293101

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.