Evidence map›Paper›PMID 39085737›Full record

ArticleClinical journal of gastroenterology2024

Biologic therapy for ulcerative colitis associated with immune thrombocytopenia.

Manabu Nagayama, Yohei Funayama, Osamu Taniguchi, Kaoru Hatano, Kunihiko Oguro, Jun Owada, Hirotsugu Sakamoto, Tomonori Yano, Randy Scott Longman, Hironori Yamamoto

Abstract readCase Reports
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In one paragraph

Article in Clinical journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Manabu NagayamaDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Yohei FunayamaDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Osamu TaniguchiDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Kaoru HatanoDivision of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Kunihiko OguroDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Jun OwadaDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Hirotsugu SakamotoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Tomonori YanoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan.
Randy Scott LongmanWeill Cornell Medicine, Jill Roberts Institute for Research in IBD, New York, NY, USA.
Hironori YamamotoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, Tochigi, Japan. ireef@jichi.ac.jp.ORCID http://orcid.org/0000-0002-3601-1153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC), a subtype of inflammatory bowel disease, occasionally manifests with extraintestinal manifestations. We present a 51-year-old male with refractory UC and immune thrombocytopenia (ITP) resistant to conventional treatments. The introduction of biologics, ustekinumab or adalimumab, resulted in clinical remission of colitis and improvements in platelet count. This case underscores the efficacy of biologics in managing refractory UC associated with ITP, emphasizing their potential to control intestinal inflammation and address concurrent thrombocytopenia, potentially avoiding surgical intervention.

Indexed as

AdalimumabColitis, UlcerativePurpura, Thrombocytopenic, IdiopathicUstekinumabHumansMaleMiddle AgedAdalimumabUstekinumabBacterial mimicryBiologicsExtraintestinal manifestationsImmune thrombocytopeniaUlcerative colitis

Identifiers

PMID39085737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.