Evidence map›Paper›PMID 39085619›Full record

ArticleJournal of neurology2024

Endovascular thrombectomy versus medical management for moderate-to-severe anterior cerebral artery occlusion stroke.

Huanwen Chen, Mihir Khunte, Ajay Malhotra, Dheeraj Gandhi, Marco Colasurdo

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Treatment outcomes of successful M1 versus M2 thrombectomy for low-ASPECTS stroke patients.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huanwen Chen *National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Mihir Khunte *Warren Alpert Medical School, Brown University, Providence, RI, USA.
Ajay MalhotraDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Dheeraj GandhiDivision of Interventional Neuroradiology, Department of Radiology, University of Maryland Medical Center, Baltimore, MD, USA.
Marco ColasurdoDepartment of Interventional Radiology, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Rd., Portland, OR, 97239, USA. colasurm@ohsu.edu.ORCID http://orcid.org/0000-0002-7823-3088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are no established patient selection criteria for endovascular thrombectomy (EVT) for anterior cerebral artery (ACA) stroke.

methodsThis was a retrospective cohort study of the 2016-2020 National Inpatient Sample in the United States. Isolated ACA-occlusion stroke patients with moderate-to-severe stroke symptoms (NIH stroke scale [NIHSS] ≥ 6) were included. Primary outcome was hospital discharge to home with self-care. Secondary outcomes include in-hospital mortality and intracranial hemorrhage (ICH). Confounders were accounted for by multivariable logistic regression.

results6685 patients were included; 335 received EVT. Compared to medical management (MM), EVT patients were younger (mean 67.2 versus 72.2 years; p = 0.014) and had higher NIHSS (mean 16.0 versus 12.5; p < 0.001). EVT was numerically but not statistically significantly associated with higher odds of home discharge compared to MM (aOR 2.26 [95%CI 0.99-5.17], p = 0.053). EVT was significantly associated with higher odds of home discharge among patients with NIHSS 10 or greater (aOR 3.35 [95%CI 1.06-10.58], p = 0.039), those who did not receive prior thrombolysis (aOR 3.96 [95%CI 1.53-10.23], p = 0.005), and those with embolic stroke etiology (aOR 4.03 [95%CI 1.21-13.47], p = 0.024). EVT was not significantly associated with higher rates of mortality (aOR 1.93 [95%CI 0.80-4.63], p = 0.14); however, it was significantly associated with higher rates of ICH (22.4% vs. 8.5%, p < 0.001).

conclusionEVT was associated with higher odds of favorable short-term outcomes for moderate-to-severe ACA-occlusion stroke in select patients. Future studies are needed to confirm the efficacy of EVT in terms of longer term neurological outcomes.

Indexed as

Endovascular ProceduresThrombectomyAgedAged, 80 and overFemaleHumansInfarction, Anterior Cerebral ArteryIschemic StrokeMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexAnterior cerebral arteryHemorrhageStrokeThrombectomyThrombolysis

Identifiers

PMID39085619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.