Evidence map›Paper›PMID 39085615›Full record

ArticleNature2024

Structural switch in acetylcholine receptors in developing muscle.

Huanhuan Li, Jinfeng Teng, Ryan E Hibbs

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Molecular organization of central cholinergic synapses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Huanhuan LiDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA.
Jinfeng TengDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA.
Ryan E HibbsDepartment of Neurobiology, University of California San Diego, La Jolla, CA, USA. rehibbs@ucsd.edu.ORCID 0000-0003-4283-1147

Funding

Structural basis of nicotinic acetylcholine receptor gating and toxin inhibitionR01NS120496 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI HIBBS, RYAN E · 2021 to 2025
$3.3M
NINDS NIH HHS R01 NS120496
6 · The paper itself

Abstract

During development, motor neurons originating in the brainstem and spinal cord form elaborate synapses with skeletal muscle fibres

Indexed as

AgingFetusMuscle DevelopmentMuscle, SkeletalReceptors, NicotinicAcetylcholineAnimalsBinding SitesCattleCryoelectron MicroscopyHumansModels, MolecularMuscle ContractionMyasthenic Syndromes, CongenitalProtein IsoformsStatic ElectricityAcetylcholineProtein IsoformsReceptors, Nicotinic

Identifiers

PMID39085615
PMCPMC12080231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.