Evidence map›Paper›PMID 39085560›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

Early screening of sleep disordered breathing in hospitalized stroke patients high-resolution pulse oximetry as prognostic and early intervention tools in patients with acute stroke and sleep apnea (HOPES TRIAL).

Sunil Sharma, Robert Stansbury, Amelia Adcock, Erica Mokaya, Mouhannad Azzouz, Kassandra Olgers, Scott Knollinger, Sijin Wen

Abstract read
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Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sunil SharmaN. Leroy Lapp Professor and Chief, Division of Pulmonary, Critical Care and Sleep Medicine, Director of MICU and Pulmonary and Sleep Medicine Program Development, Department of Medicine, WVU School of Medicine, Health Science Center North, Room 4075A, PO Box 9166, Morgantown, WV, 26506, USA. sunil.sharma@hsc.wvu.edu.ORCID 0000-0001-6006-8240
Robert StansburyN. Leroy Lapp Professor and Chief, Division of Pulmonary, Critical Care and Sleep Medicine, Director of MICU and Pulmonary and Sleep Medicine Program Development, Department of Medicine, WVU School of Medicine, Health Science Center North, Room 4075A, PO Box 9166, Morgantown, WV, 26506, USA.
Amelia AdcockDepartment of Neurology, WVU School of Medicine, Morgantown, WV, USA.
Erica MokayaWVU School of Medicine, Morgantown, WV, USA.
Mouhannad AzzouzDepartment of Neurology, WVU School of Medicine, Morgantown, WV, USA.
Kassandra OlgersN. Leroy Lapp Professor and Chief, Division of Pulmonary, Critical Care and Sleep Medicine, Director of MICU and Pulmonary and Sleep Medicine Program Development, Department of Medicine, WVU School of Medicine, Health Science Center North, Room 4075A, PO Box 9166, Morgantown, WV, 26506, USA.
Scott KnollingerDepartment of Respiratory Care, Ruby Memorial Hospital, Morgantown, WV, USA.
Sijin WenSchool of Public Health, West Virginia University, Morgantown, WV, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSleep Disordered Breathing (SDB) has been shown to increase the risk of stroke and despite recommendations, routine evaluation for SDB in acute stroke is not consistent across institutions. The necessary logistics and expertise required to conduct sleep studies in hospitalized patients remain a significant barrier. This study aims to evaluate the feasibility of high-resolution pulse-oximetry (HRPO) for the screening of SDB in acute stroke. Secondarily, considering impact of SDB on acute stroke, we investigated whether SDB at acute stroke predicts functional outcome at discharge and at 3 months post-stroke.

methodsPatients with acute mild to moderate ischemic stroke underwent an overnight HRPO within 48 h of admission. Patients were divided into SDB and no-SDB groups based on oxygen desaturations index(ODI > 10/h). Stepwise multivariate logistic regression analysis was applied to identify the relevant predictors of functional outcome (favorable [mRS 1-2 points] versus unfavorable [mrS > = 3 points]).

resultsOf the 142 consecutively screened patients, 96 were included in the analysis. Of these, 33/96 (34%) were identified as having SDB and were more likely to have unfavorable mRS scores as compared to those without SDB (odds ratio = 2.70, p-value = 0.032).

conclusionHRPO may be a low-cost and easily administered screening method to detect SDB among patients hospitalized for acute ischemic stroke. Patients with SDB (as defined by ODI) have a higher burden of neurological deficits as compared to those without SDB during hospitalization.

Indexed as

OximetryAgedAged, 80 and overEarly DiagnosisEarly Medical InterventionFemaleHospitalizationHumansIschemic StrokeMaleMiddle AgedPrognosisSleep Apnea SyndromesStrokeAcute strokeHigh-resolution pulse-oximetryModified rankin scaleSleep apnea

Identifiers

PMID39085560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.